Euglycemic Diabetic Ketoacidosis and COVID-19 Management in a Term Pregnant Patient; a Case Report

Overview

Journal Clin Case Rep

Date 2022 Dec 9

PMID 36483858

Authors

Fatemeh Mohammadzade

Behnaz Khodabakhshi

Elahe Amiri

Amir Bigdeli

Fahimeh Abdollahi

Alireza Fatemi

Affiliations

Soon will be listed here.

Abstract

In this case report, we report a Covid-19 infected female patient with gestational diabetes mellitus with primary manifestation of ketoacidosis at term pregnancy and discuss the management challenges with euglycemia and a high ketone burden.

Citing Articles

Euglycemic diabetic ketoacidosis and COVID-19 management in a term pregnant patient; a case report.

Mohammadzade F, Khodabakhshi B, Amiri E, Bigdeli A, Abdollahi F, Fatemi A Clin Case Rep. 2022; 10(12):e6705.

PMID: 36483858 PMC: 9723478. DOI: 10.1002/ccr3.6705.

References

Pikovsky M, Tan M, Ahmed A, Sykes L, Agha-Jaffar R, Yu C . Euglycaemic ketoacidosis in pregnant women with COVID-19: two case reports. BMC Pregnancy Childbirth. 2021; 21(1):427. PMC: 8207493. DOI: 10.1186/s12884-021-03928-w. View

Harman M, Cuellar E, Burkhart Denora A, Pokhriyal M, Mussarat S . Euglycemic Diabetic Ketoacidosis in a Pregnant Woman With Severe COVID-19: A Case Report. Cureus. 2022; 14(1):e21649. PMC: 8884461. DOI: 10.7759/cureus.21649. View

Gabow P . Disorders associated with an altered anion gap. Kidney Int. 1985; 27(2):472-83. DOI: 10.1038/ki.1985.34. View

Kathuria-Prakash N, Mosaferi T, Xie M, Antrim L, Angell T, In G . COVID-19 Outcomes of Patients With Differentiated Thyroid Cancer: A Multicenter Los Angeles Cohort Study. Endocr Pract. 2021; 27(2):90-94. PMC: 7831810. DOI: 10.1016/j.eprac.2020.12.013. View

Li J, Wang X, Chen J, Zuo X, Zhang H, Deng A . COVID-19 infection may cause ketosis and ketoacidosis. Diabetes Obes Metab. 2020; 22(10):1935-1941. PMC: 7264681. DOI: 10.1111/dom.14057. View

Smati S, Mahot P, Bourdiol A, Ploteau S, Hadjadj S, Cariou B . Euglycaemic ketoacidosis during gestational diabetes with concomitant COVID-19 infection. Diabetes Metab. 2020; 47(2):101181. PMC: 7387919. DOI: 10.1016/j.diabet.2020.07.008. View

Mohammadzade F, Khodabakhshi B, Amiri E, Bigdeli A, Abdollahi F, Fatemi A . Euglycemic diabetic ketoacidosis and COVID-19 management in a term pregnant patient; a case report. Clin Case Rep. 2022; 10(12):e6705. PMC: 9723478. DOI: 10.1002/ccr3.6705. View

Yao Y, Cao J, Wang Q, Shi Q, Liu K, Luo Z . D-dimer as a biomarker for disease severity and mortality in COVID-19 patients: a case control study. J Intensive Care. 2020; 8:49. PMC: 7348129. DOI: 10.1186/s40560-020-00466-z. View

Shokri P, Golmohammadi S, Noori M, Nejadghaderi S, Carson-Chahhoud K, Safiri S . The relationship between blood groups and risk of infection with SARS-CoV-2 or development of severe outcomes: A review. Rev Med Virol. 2022; 32(1):e2247. PMC: 8209917. DOI: 10.1002/rmv.2247. View

10.

Deligiorgi M, Siasos G, Vakkas L, Trafalis D . Charting the Unknown Association of COVID-19 with Thyroid Cancer, Focusing on Differentiated Thyroid Cancer: A Call for Caution. Cancers (Basel). 2021; 13(22). PMC: 8616091. DOI: 10.3390/cancers13225785. View

11.

Prentice A, Prentice A, Lamb W, Lunn P, Austin S . Metabolic consequences of fasting during Ramadan in pregnant and lactating women. Hum Nutr Clin Nutr. 1983; 37(4):283-94. View

12.

Guo R, Yang L, Li L, Zhao X . Diabetic ketoacidosis in pregnancy tends to occur at lower blood glucose levels: case-control study and a case report of euglycemic diabetic ketoacidosis in pregnancy. J Obstet Gynaecol Res. 2008; 34(3):324-30. DOI: 10.1111/j.1447-0756.2008.00720.x. View

13.

Wazir S, Shittu S, Dukhan K, Sharief M, Beer S, Malik W . Euglycemic diabetic ketoacidosis in pregnancy with COVID-19: A case report and literature review. Clin Case Rep. 2022; 10(4):e05680. PMC: 8980935. DOI: 10.1002/ccr3.5680. View

14.

Nasa P, Chaudhary S, Shrivastava P, Singh A . Euglycemic diabetic ketoacidosis: A missed diagnosis. World J Diabetes. 2021; 12(5):514-523. PMC: 8107974. DOI: 10.4239/wjd.v12.i5.514. View

15.

Kamalakannan D, Baskar V, Barton D, Abdu T . Diabetic ketoacidosis in pregnancy. Postgrad Med J. 2003; 79(934):454-7. PMC: 1742779. DOI: 10.1136/pmj.79.934.454. View

16.

Lim S, Bae J, Kwon H, Nauck M . COVID-19 and diabetes mellitus: from pathophysiology to clinical management. Nat Rev Endocrinol. 2020; 17(1):11-30. PMC: 7664589. DOI: 10.1038/s41574-020-00435-4. View

17.

van Amesfoort J, Werter D, Painter R, Hermans F . Severe metabolic ketoacidosis as a primary manifestation of SARS-CoV-2 infection in non-diabetic pregnancy. BMJ Case Rep. 2021; 14(4). PMC: 8057576. DOI: 10.1136/bcr-2021-241745. View

18.

Jaber J, Standley M, Reddy R . Euglycemic Diabetic Ketoacidosis in Pregnancy: A Case Report and Review of Current Literature. Case Rep Crit Care. 2019; 2019:8769714. PMC: 6721267. DOI: 10.1155/2019/8769714. View

19.

de Sa-Ferreira C, da Costa C, Guimaraes J, Sampaio N, Silva L, de Mascarenhas L . Diabetic ketoacidosis and COVID-19: what have we learned so far?. Am J Physiol Endocrinol Metab. 2021; 322(1):E44-E53. PMC: 8721947. DOI: 10.1152/ajpendo.00244.2021. View

20.

Thorne I, Steele S, Martineau M, Girling J . Case series of COVID-19 infection in pregnancy complicated by ketoacidosis and symptomatic breathlessness. Obstet Med. 2022; 15(1):50-53. PMC: 9008316. DOI: 10.1177/1753495X211024511. View