Non-invasive Assessment of Fatigue and Recovery of Inspiratory Rib Cage Muscles During Endurance Test in Healthy Individuals

Overview

Journal PLoS One

Specialties General Medicine
Science

Date 2022 Dec 8

PMID 36477075

Authors

Thiago Bezerra Wanderley E Lima

Antonio Sarmento

Rayane Grayce da Silva Vieira

Esmivany Lhara de Freitas Castro

Francesca Pennati

Andrea Aliverti

Vanessa Regiane Resqueti

Guilherme Augusto de Freitas Fregonezi

Affiliations

Soon will be listed here.

Abstract

Introduction: Fatigue is defined as loss of capacity to develop muscle force and/or velocity that is reversible at rest. We assessed non-invasively the fatigue and recovery of inspiratory rib cage muscles during two respiratory endurance tests in healthy individuals.

Methods: The sniff nasal inspiratory pressure (SNIP) was assessed before and after two respiratory endurance tests: normocapnic hyperpnea (NH) and inspiratory pressure threshold loading (IPTL). Contractile (maximum rate of pressure development and time to peak pressure) and relaxation parameters (maximum relaxation rate [MRR], time constant of pressure decay [τ], and half relaxation time) obtained from sniff curves and shortening velocity and mechanical power estimated using optoelectronic plethysmography were analyzed during SNIP maneuvers. Respiratory muscle activity (electromyography) and tissue oxygenation (near-infrared spectroscopy-NIRS) were obtained during endurance tests and SNIP maneuvers. Fatigue development of inspiratory rib cage muscles was assessed according to the slope of decay of median frequency.

Results: Peak pressure during SNIP decreased after both protocols (p <0.05). MRR, shortening velocity, and mechanical power decreased (p <0.05), whereas τ increased after IPTL (p <0.05). The median frequency of inspiratory rib cage muscles (i.e., sum of sternocleidomastoid, scalene, and parasternal) decreased linearly during IPTL and exponentially during NH, mainly due to the sternocleidomastoid.

Conclusion: Fatigue development behaved differently between protocols and relaxation properties (MRR and τ), shortening velocity, and mechanical power changed only in the IPTL.

Citing Articles

Ultrasonographic evaluation of diaphragm fatigue in healthy humans.

Illidi C, Romer L Exp Physiol. 2025; 110(3):478-493.

PMID: 39780750 PMC: 11868021. DOI: 10.1113/EP092322.

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