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DNTP Concentrations Do Not Increase in Mammalian Cells in Response to DNA Damage

Overview
Journal Cell Metab
Publisher Cell Press
Date 2022 Dec 8
PMID 36476929
Authors
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Abstract

A recent publication reported a uniform ∼5- to 6-fold increase in dNTP pools 30 min after exposure to ionizing radiation. Das et al. were not able to reproduce these results. Their data instead agree with earlier publications reporting no increase in dNTP pools in mammalian cells in response to DNA damage.

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