Low Acceptance Rate of COVID-19 Vaccination and Reduced Quality of Life Among Heart Transplant Recipients During the COVID-19 Pandemic

Overview

Journal J Card Surg

Specialties Cardiology & Vascular Diseases
General Surgery

Date 2022 Nov 29

PMID 36444896

Authors

Qingsong Wu

Yue Shen

Linfeng Xie

Jiaxin Zhang

Zhihuang Qiu

Mirong Tang

Liangwan Chen

Affiliations

Soon will be listed here.

Abstract

Objectives: To investigate the impact of the current coronavirus disease 2019 (COVID-19) pandemic on the quality of life (QoL) and status of COVID-19 vaccination in heart transplant recipients (HTRs).

Methods: Patients who underwent allogeneic heart transplants between June 2006 and December 2019, who survived were selected from a follow-up registration form at our center. Data were collected using questionnaires in 2021, the QoL survey was conducted using the MOS 36-item Short-Form Health Survey (SF-36) and compared to the same time frame in 2019. The patients were divided into two groups: post-epidemic (A) and pre-epidemic (B) groups. We also recorded whether the participants had been vaccinated against COVID-19 (Beijing Sinovac COVID-19 vaccine). All the data obtained were analyzed.

Results: There were 88 patients who participated in the study. Only 12 (13.6%) were vaccinated. In terms of SF-36 scale assessments, after the outbreak of the COVID-19 pandemic, Group A scored lower in vitality [52.5(49.0, 58.0) vs. 75.0(69.0, 79.0), p < .001], social functioning [54.0(50.5, 58.0) vs. 74.0(67.5, 78.0), p < .001], role emotional [58.5(55.0, 62.0) vs. 67.0(63.0, 71.0), p < .001], and mental health [58.5(55.0, 62.0) vs. 76.0(72.0, 79.0), p < .001]. In Group A the mental component summary (MCS) significantly decreased [222.0(214.5, 230.0) vs. 289.0(277.5, 299.5), p < .001]. The PCS and MCS of HTRs who had been vaccinated against COVID-19 were significantly higher than those who had not [PCS: 283.5(280.0, 287.0) vs. 276.0(271.0, 279.0), p < .001; MCS: 245.0(141.5, 254.0) vs. 220.0(213.5, 226.5), p < .001].

Conclusion: Low acceptance levels of COVID-19 vaccination were observed in the HTRs. The QoL of the HTRs decreased after the COVID-19 pandemic.

Citing Articles

Epidemiological and Clinical Characteristics of the Course of COVID-19 Among Vaccinated and Unvaccinated Heart Transplant Recipients in Slovenia.

Grasselli Kmet N, Mavric M, Saletinger R Vaccines (Basel). 2025; 12(12.

PMID: 39772027 PMC: 11680375. DOI: 10.3390/vaccines12121366.

Low acceptance rate of COVID-19 vaccination and reduced quality of life among heart transplant recipients during the COVID-19 pandemic.

Wu Q, Shen Y, Xie L, Zhang J, Qiu Z, Tang M J Card Surg. 2022; 37(12):4975-4981.

PMID: 36444896 PMC: 9877912. DOI: 10.1111/jocs.17205.

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