Psychological Impact on Healthcare Workers, General Population and Affected Individuals of SARS and COVID-19: A Systematic Review and Meta-analysis

Overview

Journal Front Public Health

Specialty Public Health

Date 2022 Nov 21

PMID 36407973

Authors

Teris Cheung

Calvin Pak Wing Cheng

Tommy Kwan Hin Fong

Nigussie Tadesse Sharew

Robert L Anders

Yu Tao Xiang

Simon Ching Lam

Affiliations

Soon will be listed here.

Abstract

Background: Any infectious disease outbreak may lead to a negative detrimental psychological impact on individuals and the community at large, however; there was no systematic review nor meta-analysis that examined the relationship between the psychological/mental health impact of SARS and COVID-19 outbreak in Asia.

Methods And Design: A systematic search was conducted using PubMed, EMBASE, Medline, PsycINFO, and CINAHL databases from 1/1/2000 to 1/6/2020. In this systematic review and meta-analysis, we analyzed the psychological impact on confirmed/suspected cases, healthcare workers and the general public during the Severe Acute Respiratory Syndrome (SARS) outbreak and Coronavirus disease (COVID-19) epidemics. Primary outcomes included prevalence of depression, anxiety, stress, post-traumatic stress disorder, aggression, sleeping problems and psychological symptoms.

Result: Twenty-three eligible studies ( = 27,325) were included. Random effect model was used to analyze the data using STATA. Of these studies, 11 were related to the SARS outbreak and 12 related to COVID-19 outbreaks. The overall prevalence rate of anxiety during SARS and COVID-19 was 37.8% (95% CI: 21.1-54.5, < 0.001, I2 = 96.9%) and 34.8% (95% CI: 29.1-40.4), respectively. For depression, the overall prevalence rate during SARS and COVID-19 was 30.9% (95% CI: 18.6-43.1, < 0.001, I2 = 97.3%) and 32.4% (95% CI: 19.8-45.0, < 0.001, I2 = 99.8%), respectively. The overall prevalence rate of stress was 9.4% (95% CI: -0.4 -19.2, = 0.015, I2 = 83.3%) and 54.1% (95% CI: 35.7-72.6, < 0.001, I2 = 98.8%) during SARS and COVID-19, respectively. The overall prevalence of PTSD was 15.1% (95% CI: 8.2-22.0, < 0.001) during SARS epidemic, calculated by random-effects model ( < 0.05), with significant between-study heterogeneity (I2 = 93.5%).

Conclusion: The SARS and COVID-19 epidemics have brought about high levels of psychological distress to individuals. Psychological interventions and contingent digital mental health platform should be promptly established nationwide for continuous surveillance of the increasing prevalence of negative psychological symptoms. Health policymakers and mental health experts should jointly collaborate to provide timely, contingent mental health treatment and psychological support to those in need to reduce the global disease burden.

Systematic Review Registration: CRD42020182787, identifier PROSPER.

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References

Lancee W, Maunder R, Goldbloom D . Prevalence of psychiatric disorders among Toronto hospital workers one to two years after the SARS outbreak. Psychiatr Serv. 2008; 59(1):91-5. PMC: 2923654. DOI: 10.1176/ps.2008.59.1.91. View

Yang S, Kwak S, Ko E, Chang M . The Mental Health Burden of the COVID-19 Pandemic on Physical Therapists. Int J Environ Res Public Health. 2020; 17(10). PMC: 7277530. DOI: 10.3390/ijerph17103723. View

Kwek S, Chew W, Ong K, Ng A, Lee L, Kaw G . Quality of life and psychological status in survivors of severe acute respiratory syndrome at 3 months postdischarge. J Psychosom Res. 2006; 60(5):513-9. PMC: 7094294. DOI: 10.1016/j.jpsychores.2005.08.020. View

Deledda G, Riccardi N, Gori S, Poli S, Giansante M, Geccherle E . The Impact of the SARS-CoV-2 Outbreak on the Psychological Flexibility and Behaviour of Cancelling Medical Appointments of Italian Patients with Pre-Existing Medical Condition: The "ImpACT-COVID-19 for Patients" Multi-Centre Observational Study. Int J Environ Res Public Health. 2021; 18(1). PMC: 7794735. DOI: 10.3390/ijerph18010340. View

Liu X, Kakade M, Fuller C, Fan B, Fang Y, Kong J . Depression after exposure to stressful events: lessons learned from the severe acute respiratory syndrome epidemic. Compr Psychiatry. 2011; 53(1):15-23. PMC: 3176950. DOI: 10.1016/j.comppsych.2011.02.003. View

Vally Z . Public perceptions, anxiety and the perceived efficacy of health-protective behaviours to mitigate the spread of the SARS-Cov-2/ COVID-19 pandemic. Public Health. 2020; 187:67-73. PMC: 7414382. DOI: 10.1016/j.puhe.2020.08.002. View

De Giacomo A, Pedaci C, Palmieri R, Simone M, Costabile A, Craig F . Psychological impact of the SARS-CoV-2 pandemic in children with neurodevelopmental disorders and their families: evaluation before and during covid-19 outbreak among an Italian sample. Riv Psichiatr. 2021; 56(4):205-210. DOI: 10.1708/3654.36348. View

Lopes D, Henriques A, Santos-Dias M, Nunes-Da-Silva C, Goncalves J, de Sousa R . Staff SARS-CoV-2 Seroprevalence and Mental Health as Key Factors in University Response to COVID-19 Pandemic. Front Public Health. 2021; 9:689919. PMC: 8241921. DOI: 10.3389/fpubh.2021.689919. View

Chatterjee S, Bhattacharyya R, Bhattacharyya S, Gupta S, Das S, Banerjee B . Attitude, practice, behavior, and mental health impact of COVID-19 on doctors. Indian J Psychiatry. 2020; 62(3):257-265. PMC: 7368446. DOI: 10.4103/psychiatry.IndianJPsychiatry_333_20. View

10.

Koh D . Occupational risks for COVID-19 infection. Occup Med (Lond). 2020; 70(1):3-5. PMC: 7107962. DOI: 10.1093/occmed/kqaa036. View

11.

Tzeng N, Chung C, Chang C, Chang H, Kao Y, Chang S . What could we learn from SARS when facing the mental health issues related to the COVID-19 outbreak? A nationwide cohort study in Taiwan. Transl Psychiatry. 2020; 10(1):339. PMC: 7538046. DOI: 10.1038/s41398-020-01021-y. View

12.

. Note from the editors: World Health Organization declares novel coronavirus (2019-nCoV) sixth public health emergency of international concern. Euro Surveill. 2020; 25(5). PMC: 7014669. DOI: 10.2807/1560-7917.ES.2020.25.5.200131e. View

13.

Higgins J, Thompson S . Quantifying heterogeneity in a meta-analysis. Stat Med. 2002; 21(11):1539-58. DOI: 10.1002/sim.1186. View

14.

Zhu J, Sun L, Zhang L, Wang H, Fan A, Yang B . Prevalence and Influencing Factors of Anxiety and Depression Symptoms in the First-Line Medical Staff Fighting Against COVID-19 in Gansu. Front Psychiatry. 2020; 11:386. PMC: 7202136. DOI: 10.3389/fpsyt.2020.00386. View

15.

Xing J, Sun N, Xu J, Geng S, Li Y . Study of the mental health status of medical personnel dealing with new coronavirus pneumonia. PLoS One. 2020; 15(5):e0233145. PMC: 7237008. DOI: 10.1371/journal.pone.0233145. View

16.

Moher D, Liberati A, Tetzlaff J, Altman D . Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med. 2009; 6(7):e1000097. PMC: 2707599. DOI: 10.1371/journal.pmed.1000097. View

17.

Wu K, Chan S, Ma T . Posttraumatic stress, anxiety, and depression in survivors of severe acute respiratory syndrome (SARS). J Trauma Stress. 2005; 18(1):39-42. PMC: 7166878. DOI: 10.1002/jts.20004. View

18.

Preti E, Di Mattei V, Perego G, Ferrari F, Mazzetti M, Taranto P . The Psychological Impact of Epidemic and Pandemic Outbreaks on Healthcare Workers: Rapid Review of the Evidence. Curr Psychiatry Rep. 2020; 22(8):43. PMC: 7350408. DOI: 10.1007/s11920-020-01166-z. View

19.

Su T, Lien T, Yang C, Su Y, Wang J, Tsai S . Prevalence of psychiatric morbidity and psychological adaptation of the nurses in a structured SARS caring unit during outbreak: a prospective and periodic assessment study in Taiwan. J Psychiatr Res. 2006; 41(1-2):119-30. PMC: 7094424. DOI: 10.1016/j.jpsychires.2005.12.006. View

20.

Nicola M, Alsafi Z, Sohrabi C, Kerwan A, Al-Jabir A, Iosifidis C . The socio-economic implications of the coronavirus pandemic (COVID-19): A review. Int J Surg. 2020; 78:185-193. PMC: 7162753. DOI: 10.1016/j.ijsu.2020.04.018. View