The State of Sergipe Contribution to GH Research: from Souza Leite to Itabaianinha Syndrome

Overview

Journal Arch Endocrinol Metab

Specialty Endocrinology

Date 2022 Nov 17

PMID 36394485

Authors

Manuel H Aguiar-Oliveira

Roberto Salvatori

Affiliations

Soon will be listed here.

Abstract

In the late 19 century, José Dantas de Souza Leite, a physician born in Sergipe, published the first detailed clinical description of acromegaly under the guidance of the French neurologist Pierre Marie. In 2014, the Brazilian Society of Endocrinology and Metabolism created the "José Dantas de Souza Leite Award", which is granted every two years to a Brazilian researcher who has contributed to the development of endocrinology. In 2022, the award was given to another physician from Sergipe, Manuel Hermínio de Aguiar Oliveira, from the Federal University of Sergipe for the description of "Itabaianinha syndrome" in a cohort of individuals with isolated GH deficiency due to a homozygous inactivating mutation in the GH-releasing hormone receptor gene. This research, which was carried out over almost 30 years, was performed in partnership with Roberto Salvatori from Johns Hopkins University and in collaboration with other researchers around the world. This review article tells the story of Souza Leite, some milestones in the history of GH, and summarizes the description of Itabaianinha syndrome.

Citing Articles

Portuguese version of the Literacy Independent Cognitive Assessment (LICA) instrument in the evaluation of individuals aged 50 years or older with Itabaianinha syndrome.

Santos L, Kellner M, Lisboa W, Faro A, Oliveira C, Batista V Arch Endocrinol Metab. 2024; 68:e230265.

PMID: 39420931 PMC: 11460966. DOI: 10.20945/2359-4292-2023-0265.

Skin assessment in congenital untreated isolated GH deficiency.

Barros-Oliveira C, de Jesus M, Campos V, Salvatori R, Araujo A, Neto R Endocrine. 2024; 84(3):1116-1124.

PMID: 38703329 DOI: 10.1007/s12020-024-03840-1.

Brain morphometry and estimation of aging brain in subjects with congenital untreated isolated GH deficiency.

Villar-Gouy K, Salmon C, Salvatori R, Kellner M, Krauss M, Rocha T J Endocrinol Invest. 2024; 47(11):2797-2807.

PMID: 38627331 DOI: 10.1007/s40618-024-02372-9.

Function and form of the shoulder in congenital and untreated growth hormone deficiency.

Santos Jr H, Silva-Albuquerque V, Salvatori R, Melo E, Oliveira-Santos A, Oliveira C Endocrine. 2023; 81(3):547-554.

PMID: 37198380 DOI: 10.1007/s12020-023-03391-x.

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