Spinal Epidural Metastasis from Cervical Cancer: Report of Two Cases and Literature Review

Overview

Journal Gynecol Oncol Rep

Publisher Elsevier

Date 2022 Nov 17

PMID 36388760

Authors

Shuai Sun

Xinyue Gong

Fuquan Zhang

Affiliations

Soon will be listed here.

Abstract

Spinal epidural metastasis(SEM) from cervical cancer is extremely rare, with only 6 cases reported in the literature, including our reported 2 cases. SEM mostly occurs in poorly differentiated carcinoma. Hematogenous spread is the primary mechanism of SEM from cervical cancer. The patients with SEM usually present with a range of clinical manifestations of nervous system because of spinal cord compression. SEM from cervical cancer indicates a late event with a poor prognosis. Local treatments mainly include surgery decompression and radiotherapy. Combining local and systemic therapy might be a better choice to prolong survival.

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