Advances in Molecular Biomarkers and Liquid Biopsy in Gliomas

Overview

Journal Neurooncol Adv

Publisher Oxford University Press

Date 2022 Nov 16

PMID 36380861

Authors

Dimitrios Mathios

Jillian Phallen

Affiliations

Soon will be listed here.

Abstract

There have been significant strides toward understanding the molecular landscape of brain cancer. These advances have been focused on analyses of the tumor microenvironment and have recently expanded to include liquid biopsies to identify molecular biomarkers noninvasively. Moving from tissue to liquid-based analyses of molecular biomarkers has been challenging and currently, there are no approved noninvasive tests that are clinically useful. However, the emerging field of molecular liquid biopsy assay development in the neuro-oncology space has great potential to revolutionize the detection and monitoring of patients with brain cancer.

Citing Articles

Assessment of the Efficacy of Circulating Tumor Cells by Liquid Biopsy in the Diagnosis and Prediction of Tumor Behavior of Gliomas: A Systematic Review.

Eugene T, Roy Sg J, S N, Rappai M Cureus. 2024; 16(2):e54101.

PMID: 38357405 PMC: 10865163. DOI: 10.7759/cureus.54101.

Advances on Liquid Biopsy Analysis for Glioma Diagnosis.

Skouras P, Markouli M, Kalamatianos T, Stranjalis G, Korkolopoulou P, Piperi C Biomedicines. 2023; 11(9).

PMID: 37760812 PMC: 10525418. DOI: 10.3390/biomedicines11092371.

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