Prognostic Factors in the Treatment of Gastric Mucosal Atypical Hyperplasia by Endoscopic Submucosal Dissection

Overview

Journal BMC Surg

Publisher Biomed Central

Specialty General Surgery

Date 2022 Nov 7

PMID 36344959

Authors

Yongping Hong

Xingxing Chen

Guofeng Li

Affiliations

Soon will be listed here.

Abstract

Background: Endoscopic submucosal dissection (ESD) is becoming increasingly popular as a treatment for precancerous lesions and early cancers of the stomach. However, there have been few studies on the factors associated with the recurrence of precancerous lesions after ESD.

Methods: To investigate the prognostic factors of gastric intraepithelial neoplasia, we retrospectively analyzed 115 patients who were treated with ESD between February 2018 and January 2020. Chi-square test and Fisher's extract test were used to select factors for further investigation, and prognostic analysis was carried out with the Kaplan-Meier method and a Cox regression model.

Results: Platelet counts (P = 0.027) and albumin levels (P = 0.011) were both lower in patients with recurrence than in patients without recurrence of gastric mucosal atypical hyperplasia after ESD.

Conclusions: This study reveals that low platelet counts and albumin levels were probably unfavorable prognostic factors in mucosal atypical hyperplasia of the stomach.

Citing Articles

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Yu X, Song X, Xie Y, Zhang S, Guo J Int J Mol Sci. 2023; 24(1).

PMID: 36613767 PMC: 9820402. DOI: 10.3390/ijms24010322.

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