Transcatheter Mitral Valve Repair is Feasible and Effective in Oldest-old Patients: Results from Real-world Cohort

Overview

Journal J Geriatr Cardiol

Specialty Geriatrics

Date 2022 Nov 7

PMID 36338281

Authors

Mhd Nawar Alachkar

Annemarie Kirschfink

Anas Alnaimi

Jorg Schroder

Felix Vogt

Nikolaus Marx

Ertunc Altiok

Mohammad Almalla

Affiliations

Soon will be listed here.

Abstract

Objective: To evaluate the safety and efficacy of transcatheter mitral valve repair (TMVR) using MitraClip devices in oldest-old patients compared to younger patients.

Methods: The study retrospectively included 340 consecutive patients who underwent TMVR. Patients were classified according to age into the oldest-old (age ≥ 85 years) patient group or the younger (age < 85 years) patient group. Immediate results of the procedure, intrahospital outcomes and one-year outcomes were compared.

Results: Oldest-old patients represented 15.9% ( = 54) of all patients. Procedure success was comparable for the oldest-old patient group and the younger patient group (92.6% 95.8%, = 0.30), and there was no difference in intrahospital mortality (9.2% 4.2%, = 0.12). At a one-year follow-up (interquartile range: 6-16 months), there was no significant difference in rehospitalization due to decompensated heart failure (25.5% 34.3%, = 0.24) or all-cause mortality (29.8% 22.2%, = 0.26) between the oldest-old patient group and the younger patient group. In patients with available echocardiographic follow-up, severity of residual mitral regurgitation was also comparable between the oldest-old patient group and the younger patient group.

Conclusions: TMVR seems to be feasible and effective in oldest-old patients and should be considered for oldest-old patients presenting with symptomatic severe mitral regurgitation and high surgical risk.

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