A Review of Omics Studies on Arboviruses: Alphavirus, Orthobunyavirus and Phlebovirus

Overview

Journal Viruses

Publisher MDPI

Specialty Microbiology

Date 2022 Oct 27

PMID 36298749

Authors

Rafaela Dos S Peinado

Raphael J Eberle

Raghuvir K Arni

Monika A Coronado

Affiliations

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Abstract

Since the intricate and complex steps in pathogenesis and host-viral interactions of arthropod-borne viruses or arboviruses are not completely understood, the multi-omics approaches, which encompass proteomics, transcriptomics, genomics and metabolomics network analysis, are of great importance. We have reviewed the omics studies on mosquito-borne viruses of the , and families, specifically for Chikungunya, Mayaro, Oropouche and Rift Valley Fever viruses. Omics studies can potentially provide a new perspective on the pathophysiology of arboviruses, contributing to a better comprehension of these diseases and their effects and, hence, provide novel insights for the development of new antiviral drugs or therapies.

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