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Secondary Metabolites Produced by Plant Growth-Promoting Bacterial Endophytes

Overview
Journal Microorganisms
Specialty Microbiology
Date 2022 Oct 27
PMID 36296283
Authors
Zareen Narayanan
Bernard R Glick
Affiliations
Soon will be listed here.
Abstract

There is an increasing interest in the use of beneficial microorganisms as alternatives to chemically synthesized or plant-derived molecules to produce therapeutic agents. Bacterial endophytes are plant-associated microorganisms that can colonize different parts of living plants without causing any diseases. Diverse endophytic bacteria possess the ability to synthesize a wide range of secondary metabolites with unique chemical structures that have been exploited for their anti-microbial, antiviral, anti-cancer, and anti-inflammatory properties. Additionally, production of these bioactive compounds can also benefit the host plant as they may play a significant role in a plant's interaction with the environment for adaptation and defense. As a result of their significant impact as curative compounds or as precursors to produce new drugs, the biotechnological possibilities of secondary metabolites derived from endophytic bacteria are immense.

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References
1.
Ezra D, Castillo U, Strobel G, Hess W, Porter H, Jensen J . Coronamycins, peptide antibiotics produced by a verticillate Streptomyces sp. (MSU-2110) endophytic on Monstera sp. Microbiology (Reading). 2004; 150(Pt 4):785-793. DOI: 10.1099/mic.0.26645-0. View
2.
Zhao K, Penttinen P, Guan T, Xiao J, Chen Q, Xu J . The diversity and anti-microbial activity of endophytic actinomycetes isolated from medicinal plants in Panxi plateau, China. Curr Microbiol. 2010; 62(1):182-90. DOI: 10.1007/s00284-010-9685-3. View
3.
Kim N, Shin J, Kim W, Hwang B, Kim B, Hong Y . Cytotoxic 6-alkylsalicylic acids from the endophytic Streptomyces laceyi. J Antibiot (Tokyo). 2007; 59(12):797-800. DOI: 10.1038/ja.2006.105. View
4.
Pandey S, Singh S, Vivek Babu C, Shanker K, Srivastava N, Kalra A . Endophytes of opium poppy differentially modulate host plant productivity and genes for the biosynthetic pathway of benzylisoquinoline alkaloids. Planta. 2016; 243(5):1097-114. DOI: 10.1007/s00425-016-2467-9. View
5.
Shahzad R, Waqas M, Khan A, Asaf S, Khan M, Kang S . Seed-borne endophytic Bacillus amyloliquefaciens RWL-1 produces gibberellins and regulates endogenous phytohormones of Oryza sativa. Plant Physiol Biochem. 2016; 106:236-43. DOI: 10.1016/j.plaphy.2016.05.006. View