Maintenance of Spermatogenesis Induced by HMG Treatment by Means of Continuous HCG Treatment in Hypogonadotrophic Men

Overview

Journal Acta Endocrinol (Copenh)

Specialty Endocrinology

Date 1978 Dec 1

PMID 362785

Citations 6

Authors

S G JOHNSEN

Affiliations

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Abstract

In a long-term hypophysectomized male HCG treatment was unable to initiate spermatogenesis. However, a spermatogenesis induced by HMG/HCG treatment could be maintained by HCG alone for 7 years with clinical fertility. In another hypogonadotrophic male HCG was also unable to initiate spermatogenesis. But a spermatogenesis once induced by HMG/HCG treatment could be maintained for more than one year with HCG alone. It is suggested that gonadotrophin treatment of the hypogonadotrophic male should consist of HMG + HCG until complete spermatogenesis is induced followed by maintenance treatment with HCG.

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