The Research Progress in the Interaction Between and Cancers

Overview

Journal Front Microbiol

Specialty Microbiology

Date 2022 Oct 17

PMID 36246294

Authors

Dalang Yu

Zhiping Liu

Affiliations

Soon will be listed here.

Abstract

is an opportunistic pathogenic fungus, which tends to infect the host with defective immune function including cancer patients. A growing number of studies have shown that infection increases the host susceptibility to cancer such as oral, gastric, and colorectal cancer. Cancer and anti-cancer treatment may also affect the colonization of may promote the development of cancer by damaging mucosal epithelium, inducing the production of carcinogens, triggering chronic inflammation including Th17 cell-mediated immune response. In this article, we aim to elaborate the interaction between and cancers development and summarize the potential molecular mechanisms, so as to provide theoretical basis for prevention, diagnosis and treatment of cancers.

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References

Schottenfeld D, Beebe-Dimmer J . The cancer burden attributable to biologic agents. Ann Epidemiol. 2014; 25(3):183-7. DOI: 10.1016/j.annepidem.2014.11.016. View

Ueta E, Tanida T, Yoneda K, Yamamoto T, Osaki T . Increase of Candida cell virulence by anticancer drugs and irradiation. Oral Microbiol Immunol. 2001; 16(4):243-9. DOI: 10.1034/j.1399-302x.2001.160408.x. View

Maza P, Bonfim-Melo A, Padovan A, Mortara R, Orikaza C, Ramos L . : The Ability to Invade Epithelial Cells and Survive under Oxidative Stress Is Unlinked to Hyphal Length. Front Microbiol. 2017; 8:1235. PMC: 5511855. DOI: 10.3389/fmicb.2017.01235. View

Yang P, Zhang X, Xu R, Adeel K, Lu X, Chen M . Fungal Microbiota Dysbiosis and Ecological Alterations in Gastric Cancer. Front Microbiol. 2022; 13:889694. PMC: 9100745. DOI: 10.3389/fmicb.2022.889694. View

Walter L, Canup B, Pujada A, Bui T, Arbasi B, Laroui H . Matrix metalloproteinase 9 (MMP9) limits reactive oxygen species (ROS) accumulation and DNA damage in colitis-associated cancer. Cell Death Dis. 2020; 11(9):767. PMC: 7498454. DOI: 10.1038/s41419-020-02959-z. View

Li J, Zeng M, Yan K, Yang Y, Li H, Xu X . IL-17 promotes hepatocellular carcinoma through inhibiting apoptosis induced by IFN-γ. Biochem Biophys Res Commun. 2019; 522(2):525-531. DOI: 10.1016/j.bbrc.2019.11.134. View

Wakharde A, Halbandge S, Phule D, Karuppayil S . Anticancer Drugs as Antibiofilm Agents in Candida albicans: Potential Targets. Assay Drug Dev Technol. 2018; 16(5):232-246. DOI: 10.1089/adt.2017.826. View

Mizuno R, Kawada K, Sakai Y . Prostaglandin E2/EP Signaling in the Tumor Microenvironment of Colorectal Cancer. Int J Mol Sci. 2019; 20(24). PMC: 6940958. DOI: 10.3390/ijms20246254. View

Aykut B, Pushalkar S, Chen R, Li Q, Abengozar R, Kim J . The fungal mycobiome promotes pancreatic oncogenesis via activation of MBL. Nature. 2019; 574(7777):264-267. PMC: 6858566. DOI: 10.1038/s41586-019-1608-2. View

10.

Li Y, He J, Wang F, Wang X, Yang F, Zhao C . Role of MMP-9 in epithelial-mesenchymal transition of thyroid cancer. World J Surg Oncol. 2020; 18(1):181. PMC: 7376963. DOI: 10.1186/s12957-020-01958-w. View

11.

Dong Z, Guo S, Wang Y, Zhang J, Luo H, Zheng G . USP19 Enhances MMP2/MMP9-Mediated Tumorigenesis in Gastric Cancer. Onco Targets Ther. 2020; 13:8495-8510. PMC: 7457554. DOI: 10.2147/OTT.S240543. View

12.

Nasry W, Rodriguez-Lecompte J, Martin C . Role of COX-2/PGE2 Mediated Inflammation in Oral Squamous Cell Carcinoma. Cancers (Basel). 2018; 10(10). PMC: 6211032. DOI: 10.3390/cancers10100348. View

13.

Perera M, Al-Hebshi N, Perera I, Ipe D, Ulett G, Speicher D . A dysbiotic mycobiome dominated by is identified within oral squamous-cell carcinomas. J Oral Microbiol. 2017; 9(1):1385369. PMC: 5678454. DOI: 10.1080/20002297.2017.1385369. View

14.

Furlaneto M, Favero D, Franca E, Furlaneto-Maia L . Effects of human blood red cells on the haemolytic capability of clinical isolates of Candida tropicalis. J Biomed Sci. 2015; 22:13. PMC: 4329199. DOI: 10.1186/s12929-015-0120-8. View

15.

Hafed L, Farag H, El-Rouby D, Shaker O, Shabaan H . Candida Albicans Alcohol Dehydrogenase 1 gene in oral dysplasia and oral squamous cell carcinoma. Pol J Pathol. 2019; 70(3):210-216. DOI: 10.5114/pjp.2019.90398. View

16.

Mizumoto A, Ohashi S, Hirohashi K, Amanuma Y, Matsuda T, Muto M . Molecular Mechanisms of Acetaldehyde-Mediated Carcinogenesis in Squamous Epithelium. Int J Mol Sci. 2017; 18(9). PMC: 5618592. DOI: 10.3390/ijms18091943. View

17.

Karpisheh V, Nikkhoo A, Hojjat-Farsangi M, Namdar A, Azizi G, Ghalamfarsa G . Prostaglandin E2 as a potent therapeutic target for treatment of colon cancer. Prostaglandins Other Lipid Mediat. 2019; 144:106338. DOI: 10.1016/j.prostaglandins.2019.106338. View

18.

Klimesova K, Jiraskova Zakostelska Z, Tlaskalova-Hogenova H . Oral Bacterial and Fungal Microbiome Impacts Colorectal Carcinogenesis. Front Microbiol. 2018; 9:774. PMC: 5920026. DOI: 10.3389/fmicb.2018.00774. View

19.

Chang S . T helper 17 (Th17) cells and interleukin-17 (IL-17) in cancer. Arch Pharm Res. 2019; 42(7):549-559. DOI: 10.1007/s12272-019-01146-9. View

20.

Lo Muzio L, Campisi G, Farina A, Rubini C, Pastore L, Giannone N . Effect of p63 expression on survival in oral squamous cell carcinoma. Cancer Invest. 2007; 25(6):464-9. DOI: 10.1080/07357900701509387. View