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The Role of the Stroma in Tumor Angiogenesis and Progression: The Fundamental Contribution of Pietro M. Gullino

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Specialty Molecular Biology
Date 2022 Sep 26
PMID 36161405
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Abstract

The tumor stroma is the major factor influencing the growth of cancer. It is implicated in the regulation of tumor growth and metastatic potential and impacts the outcome of therapy. This article summarizes the fundamental contribution of the Italian scientist Pietro M. Gullino in the study of tumor stroma through the development of new experimental techniques and the characterization of novel angiogenic factors.

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