Role of Immune Cells and Receptors in Cancer Treatment: An Immunotherapeutic Approach

Overview

Journal Vaccines (Basel)

Date 2022 Sep 23

PMID 36146572

Authors

Anirban Goutam Mukherjee

Uddesh Ramesh Wanjari

Arunraj Namachivayam

Reshma Murali

D S Prabakaran

Raja Ganesan

Kaviyarasi Renu

Abhijit Dey

Balachandar Vellingiri

Gnanasambandan Ramanathan

George Priya Doss C

Abilash Valsala Gopalakrishnan

Affiliations

Soon will be listed here.

Abstract

Cancer immunotherapy moderates the immune system's ability to fight cancer. Due to its extreme complexity, scientists are working to put together all the puzzle pieces to get a clearer picture of the immune system. Shreds of available evidence show the connection between cancer and the immune system. Immune responses to tumors and lymphoid malignancies are influenced by B cells, γδT cells, NK cells, and dendritic cells (DCs). Cancer immunotherapy, which encompasses adoptive cancer therapy, monoclonal antibodies (mAbs), immune checkpoint therapy, and CART cells, has revolutionized contemporary cancer treatment. This article reviews recent developments in immune cell regulation and cancer immunotherapy. Various options are available to treat many diseases, particularly cancer, due to the progress in various immunotherapies, such as monoclonal antibodies, recombinant proteins, vaccinations (both preventative and curative), cellular immunotherapies, and cytokines.

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