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Gnanasambandan Ramanathan

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Articles 35
Citations 88
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Recent Articles
1.
Das S, Ravi H, Devi Rajeswari V, Venkatraman G, Ramasamy M, Dhanasekaran S, et al.
Adv Protein Chem Struct Biol . 2025 Jan; 143():1-37. PMID: 39843133
Hepatocyte nuclear factor 4-alpha (HNF4α), a well-preserved member of the nuclear receptor superfamily of transcription factors, is found in the liver. It is recognized as a central controller of gene...
2.
Dhanasekaran S, Selvadoss P, Manoharan S, Jeyabalan S, Muthu Laxmi V, Choudhury A, et al.
Cell Biochem Biophys . 2024 Dec; PMID: 39638981
Breast cancer (BC) is the most prevalent malignancy among women globally and the leading cause of cancer-related mortality. Consequently, there is an urgent need for new, effective treatment strategies for...
3.
Das S, Devi Rajeswari V, Venkatraman G, Ramanathan G
Cell Biochem Biophys . 2024 Nov; PMID: 39537915
Parkinson's disease (PD) is a complex neurodegenerative disorder marked by the progressive loss of dopaminergic neurons in the substantia nigra. While current treatments primarily manage symptoms, there is increasing interest...
4.
Dhanasekaran S, Jeyabalan S, Choudhury A, Rajeswari V, Ramanathan G, Thamaraikani T, et al.
Cell Biochem Biophys . 2024 Oct; PMID: 39384699
Type 2 diabetes (T2D), also known as non-insulin-dependent diabetes mellitus, represents the prevailing manifestation of diabetes, encompassing a substantial majority of cases, ~90-95%. Plant-derived antidiabetic leads are being intensively explored...
5.
Das S, Ramanathan G
J Cell Biochem . 2024 Sep; 126(1):e30661. PMID: 39344977
Diabetic Kidney Disease (DKD), a frequent consequence of diabetes, has substantial implications for both morbidity and mortality rates, prompting the exploration of new metabolic biomarkers due to limitations in current...
6.
Das S, Ravi H, Babu A, Banerjee M, Kanagavalli R, Dhanasekaran S, et al.
Adv Protein Chem Struct Biol . 2024 Jul; 142:293-328. PMID: 39059989
Type 2 diabetes mellitus (T2DM) is a worldwide health problem that has raised major concerns to the public health community. This chronic condition typically results from the cell's inability to...
7.
Ravi H, Das S, Devi Rajeswari V, Venkatraman G, Choudhury A, Chakraborty S, et al.
Adv Protein Chem Struct Biol . 2024 Jul; 142:257-291. PMID: 39059988
Diabetes constitutes a significant global public health challenge that is rapidly reaching epidemic proportions. Among the non-communicable diseases, the incidence of diabetes is rising at an alarming rate. The International...
8.
Dhanasekaran S, Selvadoss P, Manoharan S, Jeyabalan S, Yaraguppi D, Choudhury A, et al.
Cell Biochem Biophys . 2024 Jul; 82(3):2473-2492. PMID: 39042185
Chronic hepatitis caused by the hepatitis C virus (HCV) is closely linked with the advancement of liver disease. The research hypothesis suggests that the NS5B enzyme (non-structural 5B protein) of...
9.
Banerjee R, Maitra I, Bhattacharya T, Banerjee M, Ramanathan G, Rayala S, et al.
Crit Rev Oncol Hematol . 2024 Jun; 201:104417. PMID: 38901639
Triple-negative breast carcinoma (TNBC) is one of the most challenging subtypes of breast carcinoma and it has very limited therapeutic options as it is highly aggressive. The prognostic biomarkers are...
10.
Venugopal D, Viswanathan P, Ravindran S, Punnoose A, Yasasve M, Dicky John D, et al.
Mol Biol Rep . 2024 Feb; 51(1):303. PMID: 38356030
Background: This study aimed to assess silymarin's anticancer and antifibrotic potential through in silico analysis and investigate its impact on in vitro arecoline-induced fibrosis in primary human buccal fibroblasts (HBF)....