MicroRNA398: A Master Regulator of Plant Development and Stress Responses

Overview

Journal Int J Mol Sci

Publisher MDPI

Specialties Biochemistry
Chemistry
Molecular Biology

Date 2022 Sep 23

PMID 36142715

Authors

Jing Li

Qiaoqiao Song

Zhi-Fang Zuo

Lin Liu

Affiliations

Soon will be listed here.

Abstract

MicroRNAs (miRNAs) play crucial roles in plant development and stress responses, and a growing number of studies suggest that miRNAs are promising targets for crop improvement because they participate in the regulation of diverse, important agronomic traits. MicroRNA398 (miR398) is a conserved miRNA in plants and has been shown to control multiple stress responses and plant growth in a variety of species. There are many studies on the stress response and developmental regulation of miR398. To systematically understand its function, it is necessary to summarize the evolution and functional roles of miR398 and its target genes. In this review, we analyze the evolution of miR398 in plants and outline its involvement in abiotic and biotic stress responses, in growth and development and in model and non-model plants. We summarize recent functional analyses, highlighting the role of miR398 as a master regulator that coordinates growth and diverse responses to environmental factors. We also discuss the potential for fine-tuning miR398 to achieve the goal of simultaneously improving plant growth and stress tolerance.

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References

Luan Y, Wang W, Liu P . Identification and functional analysis of novel and conserved microRNAs in tomato. Mol Biol Rep. 2014; 41(8):5385-94. DOI: 10.1007/s11033-014-3410-4. View

Zhang H, Zhang J, Yan J, Gou F, Mao Y, Tang G . Short tandem target mimic rice lines uncover functions of miRNAs in regulating important agronomic traits. Proc Natl Acad Sci U S A. 2017; 114(20):5277-5282. PMC: 5441788. DOI: 10.1073/pnas.1703752114. View

Tiwari J, Buckseth T, Zinta R, Saraswati A, Singh R, Rawat S . Genome-wide identification and characterization of microRNAs by small RNA sequencing for low nitrogen stress in potato. PLoS One. 2020; 15(5):e0233076. PMC: 7237020. DOI: 10.1371/journal.pone.0233076. View

Perea-Garcia A, Andres-Borderia A, Huijser P, Penarrubia L . The Copper-microRNA Pathway Is Integrated with Developmental and Environmental Stress Responses in . Int J Mol Sci. 2021; 22(17). PMC: 8430956. DOI: 10.3390/ijms22179547. View

Xu W, Meng Y, Wise R . Mla- and Rom1-mediated control of microRNA398 and chloroplast copper/zinc superoxide dismutase regulates cell death in response to the barley powdery mildew fungus. New Phytol. 2013; 201(4):1396-1412. DOI: 10.1111/nph.12598. View

Higashi Y, Takechi K, Takano H, Takio S . Involvement of microRNA in copper deficiency-induced repression of chloroplastic CuZn-superoxide dismutase genes in the moss Physcomitrella patens. Plant Cell Physiol. 2013; 54(8):1345-55. DOI: 10.1093/pcp/pct084. View

Jia X, Wang W, Ren L, Chen Q, Mendu V, Willcut B . Differential and dynamic regulation of miR398 in response to ABA and salt stress in Populus tremula and Arabidopsis thaliana. Plant Mol Biol. 2009; 71(1-2):51-9. DOI: 10.1007/s11103-009-9508-8. View

Yamasaki H, Abdel-Ghany S, Cohu C, Kobayashi Y, Shikanai T, Pilon M . Regulation of copper homeostasis by micro-RNA in Arabidopsis. J Biol Chem. 2007; 282(22):16369-78. DOI: 10.1074/jbc.M700138200. View

Chu C, Lee W, Guo W, Pan S, Chen L, Li H . A copper chaperone for superoxide dismutase that confers three types of copper/zinc superoxide dismutase activity in Arabidopsis. Plant Physiol. 2005; 139(1):425-36. PMC: 1203391. DOI: 10.1104/pp.105.065284. View

10.

Takeda S, Matsuoka M . Genetic approaches to crop improvement: responding to environmental and population changes. Nat Rev Genet. 2008; 9(6):444-57. DOI: 10.1038/nrg2342. View

11.

Sunkar R, Kapoor A, Zhu J . Posttranscriptional induction of two Cu/Zn superoxide dismutase genes in Arabidopsis is mediated by downregulation of miR398 and important for oxidative stress tolerance. Plant Cell. 2006; 18(8):2051-65. PMC: 1533975. DOI: 10.1105/tpc.106.041673. View

12.

Zhao H, Sun R, Albrecht U, Padmanabhan C, Wang A, Coffey M . Small RNA profiling reveals phosphorus deficiency as a contributing factor in symptom expression for citrus huanglongbing disease. Mol Plant. 2013; 6(2):301-10. PMC: 3716302. DOI: 10.1093/mp/sst002. View

13.

Zhan J . Get out and stay out: spatiotemporally regulated miR398 biogenesis enables proper ovule development. Plant Cell. 2022; 33(5):1403-1404. PMC: 8254499. DOI: 10.1093/plcell/koab054. View

14.

Li Y, Zheng Y, Addo-Quaye C, Zhang L, Saini A, Jagadeeswaran G . Transcriptome-wide identification of microRNA targets in rice. Plant J. 2010; 62(5):742-59. DOI: 10.1111/j.1365-313X.2010.04187.x. View

15.

Cai H, Liu L, Zhang M, Chai M, Huang Y, Chen F . Spatiotemporal control of miR398 biogenesis, via chromatin remodeling and kinase signaling, ensures proper ovule development. Plant Cell. 2021; 33(5):1530-1553. PMC: 8254498. DOI: 10.1093/plcell/koab056. View

16.

Yu X, Wang H, Lu Y, de Ruiter M, Cariaso M, Prins M . Identification of conserved and novel microRNAs that are responsive to heat stress in Brassica rapa. J Exp Bot. 2011; 63(2):1025-38. PMC: 3254694. DOI: 10.1093/jxb/err337. View

17.

Kantar M, Lucas S, Budak H . miRNA expression patterns of Triticum dicoccoides in response to shock drought stress. Planta. 2010; 233(3):471-84. DOI: 10.1007/s00425-010-1309-4. View

18.

Li Z, Xu H, Li Y, Wan X, Ma Z, Cao J . Analysis of physiological and miRNA responses to Pi deficiency in alfalfa (Medicago sativa L.). Plant Mol Biol. 2018; 96(4-5):473-492. DOI: 10.1007/s11103-018-0711-3. View

19.

Jamla M, Joshi S, Patil S, Tripathi B, Kumar V . MicroRNAs modulating nutrient homeostasis: a sustainable approach for developing biofortified crops. Protoplasma. 2022; 260(1):5-19. DOI: 10.1007/s00709-022-01775-w. View

20.

Li Y, Li X, Yang J, He Y . Natural antisense transcripts of MIR398 genes suppress microR398 processing and attenuate plant thermotolerance. Nat Commun. 2020; 11(1):5351. PMC: 7582911. DOI: 10.1038/s41467-020-19186-x. View