Usefulness of Hepatobiliary Scintigraphy for Predicting Late Complications in Patients with Choledochal Cysts

Overview

Journal Pediatr Surg Int

Specialties General Surgery
Pediatrics

Date 2022 Sep 20

PMID 36125544

Authors

Yunosuke Kawaguchi

Keita Terui

Shugo Komatsu

Mitsuyuki Nakata

Ryohei Shibata

Hiroko Yoshizawa

Tomoya Hirokawa

Erika Nakatani

Tomoro Hishiki

Affiliations

Soon will be listed here.

Abstract

Purpose: Hepatobiliary scintigraphy is a minimally invasive imaging method that evaluates bile flow dynamics. At our hospital, it has been performed for postoperative evaluation of patients with choledochal cysts (CC). This study evaluated the usefulness of biliary scintigraphy for predicting late complications in patients with CCs.

Methods: The study included pediatric patients with CC who underwent surgery at Chiba University Hospital from 1978 to 2020, followed by postoperative biliary scintigraphy and subsequent radiologic evaluation. The patients were divided into two groups according to the presence or absence of "biliary cholestasis" on biliary scintigraphy.

Results: The study included 108 patients, with a median age at surgery of 2 years and 11 months. The median follow-up period was 5203 days, with 11 hepatolithiasis cases and 8 cholangitis cases. No patients had cholangiocarcinoma. Twelve patients were considered to have "cholestasis" following biliary scintigraphy evaluation. There was no significant difference in the occurrence of hepatolithiasis between the cholestasis and non-cholestasis groups (p = 0.47), but cholangitis was significantly more common in the cholestasis group (p = 0.016).

Conclusion: Biliary cholestasis on postoperative hepatobiliary scintigraphy was a risk factor for cholangitis in patients with CCs. These particular patients should be monitored carefully.

Citing Articles

Characteristics and outcomes of minimally invasive surgery for congenital biliary dilatation in children aged <6 years: Comparison between children and adults.

Nakagawa Y, Uchida H, Shirota C, Tainaka T, Makita S, Satomi M J Hepatobiliary Pancreat Sci. 2024; 31(12):876-885.

PMID: 39245879 PMC: 11660993. DOI: 10.1002/jhbp.12069.

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