Atypical Acute Disseminated Encephalomyelitis with Systemic Inflammation After a First Dose of AztraZaneca COVID-19 Vaccine. A Case Report

Overview

Journal Front Neurol

Specialty Neurology

Date 2022 Sep 15

PMID 36105772

Authors

Laure Bastide

Gaetano Perrotta

Valentina Lolli

Celine Mathey

Ortensa-Irina Vierasu

Serge Goldman

Frederic Vandergheynst

Affiliations

Soon will be listed here.

Abstract

Background: Only a few cases of acute disseminated encephalomyelitis (ADEM) following coronavirus disease 19 (COVID-19) vaccination have been described since the beginning of the vaccination campaign.

Results: Here we report the first case of central nervous system (CNS) demyelination with systemic inflammatory findings on whole body 19-fluorodeoxyglucose positron emission tomography with computed tomography (FDG-PET/CT) following the ChAdOx1 nCoV-19 vaccine.

Conclusions: Clinicians should stay aware of potential new adverse events after immunization.

Citing Articles

The Occurrence of Acute Disseminated Encephalomyelitis in SARS-CoV-2 Infection/Vaccination: Our Experience and a Systematic Review of the Literature.

Stoian A, Bajko Z, Stoian M, Cioflinc R, Niculescu R, Arbanasi E Vaccines (Basel). 2023; 11(7).

PMID: 37515041 PMC: 10385010. DOI: 10.3390/vaccines11071225.

Neurological Disorders following COVID-19 Vaccination.

Yang Y, Huang L Vaccines (Basel). 2023; 11(6).

PMID: 37376503 PMC: 10302665. DOI: 10.3390/vaccines11061114.

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