Neutrophil Extracellular Traps: New Players in Cancer Research

Overview

Journal Front Immunol

Specialty Allergy & Immunology

Date 2022 Sep 5

PMID 36059520

Authors

Junjie Zhao

Jiaqi Jin

Affiliations

Soon will be listed here.

Abstract

NETs are chromatin-derived webs extruded from neutrophils as a result of either infection or sterile stimulation using chemicals, cytokines, or microbes. In addition to the classical role that NETs play in innate immunity against infection and injuries, NETs have been implicated extensively in cancer progression, metastatic dissemination, and therapy resistance. The purpose of this review is to describe recent investigations into NETs and the roles they play in tumor biology and to explore their potential as therapeutic targets in cancer treatment.

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