Vitamin D and the Kidney: Two Players, One Console

Overview

Journal Int J Mol Sci

Publisher MDPI

Specialties Biochemistry
Chemistry
Molecular Biology

Date 2022 Aug 26

PMID 36012412

Authors

Fulvia Zappulo

Maria Cappuccilli

Alessandra Cingolani

Anna Scrivo

Anna Laura Croci Chiocchini

Miriam Di Nunzio

Chiara Donadei

Marianna Napoli

Francesco Tondolo

Giuseppe Cianciolo

Gaetano La Manna

Affiliations

Soon will be listed here.

Abstract

Vitamin D belongs to the group of liposoluble steroids mainly involved in bone metabolism by modulating calcium and phosphorus absorption or reabsorption at various levels, as well as parathyroid hormone production. Recent evidence has shown the extra-bone effects of vitamin D, including glucose homeostasis, cardiovascular protection, and anti-inflammatory and antiproliferative effects. This narrative review provides an overall view of vitamin D's role in different settings, with a special focus on chronic kidney disease and kidney transplant.

Citing Articles

VITAMIN D DEFICIENCY, BONE TURNOVER MARKERS AND ARTERIAL CALCIFICATIONS IN NON-DIALYSIS CHRONIC KIDNEY DISEASE PATIENTS.

Chiriac C, Ciurea O, Lipan M, Capusa C, Mircescu G Acta Endocrinol (Buchar). 2024; 20(1):12-20.

PMID: 39372299 PMC: 11449234. DOI: 10.4183/aeb.2024.12.

Target Values for 25-Hydroxy and 1,25-Dihydroxy Vitamin D Based on Their Associations with Inflammation and Calcium-Phosphate Metabolism.

Li X, Liu Y, Chen X, Reichetzeder C, Elitok S, Kramer B Nutrients. 2024; 16(16).

PMID: 39203816 PMC: 11357189. DOI: 10.3390/nu16162679.

Development and validation of a nomogram to predict protein-energy wasting in patients with peritoneal dialysis: a multicenter cohort study.

Mei Z, Zhu B, Sun X, Zhou Y, Qiu Y, Ye X PeerJ. 2023; 11:e15507.

PMID: 37304869 PMC: 10249631. DOI: 10.7717/peerj.15507.

The Role of Vitamin D in Reducing the Risk of Metabolic Disturbances That Cause Cardiovascular Diseases.

Al-Oanzi Z, Alenazy F, Alhassan H, Alruwaili Y, Alessa A, Alfarm N J Cardiovasc Dev Dis. 2023; 10(5).

PMID: 37233176 PMC: 10219128. DOI: 10.3390/jcdd10050209.

Role of nutritional vitamin D in chronic kidney disease-mineral and bone disorder: A narrative review.

Shen Y Medicine (Baltimore). 2023; 102(14):e33477.

PMID: 37026958 PMC: 10082266. DOI: 10.1097/MD.0000000000033477.

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