» Articles » PMID: 35977957

Lightweight Distributed Provenance Model for Complex Real-world Environments

Overview
Journal Sci Data
Specialty Science
Date 2022 Aug 17
PMID 35977957
Authors
Affiliations
Soon will be listed here.
Abstract

Provenance is information describing the lineage of an object, such as a dataset or biological material. Since these objects can be passed between organizations, each organization can document only parts of the objects life cycle. As a result, interconnection of distributed provenance parts forms distributed provenance chains. Dependant on the actual provenance content, complete provenance chains can provide traceability and contribute to reproducibility and FAIRness of research objects. In this paper, we define a lightweight provenance model based on W3C PROV that enables generation of distributed provenance chains in complex, multi-organizational environments. The application of the model is demonstrated with a use case spanning several steps of a real-world research pipeline - starting with the acquisition of a specimen, its processing and storage, histological examination, and the generation/collection of associated data (images, annotations, clinical data), ending with training an AI model for the detection of tumor in the images. The proposed model has become an open conceptual foundation of the currently developed ISO 23494 standard on provenance for biotechnology domain.

Citing Articles

Recording provenance of workflow runs with RO-Crate.

Leo S, Crusoe M, Rodriguez-Navas L, Sirvent R, Kanitz A, De Geest P PLoS One. 2024; 19(9):e0309210.

PMID: 39255315 PMC: 11386446. DOI: 10.1371/journal.pone.0309210.


Provenance Information for Biomedical Data and Workflows: Scoping Review.

Gierend K, Kruger F, Genehr S, Hartmann F, Siegel F, Waltemath D J Med Internet Res. 2024; 26:e51297.

PMID: 39178413 PMC: 11380065. DOI: 10.2196/51297.


Artificial intelligence based data curation: enabling a patient-centric European health data space.

de Zegher I, Norak K, Steiger D, Muller H, Kalra D, Scheenstra B Front Med (Lausanne). 2024; 11:1365501.

PMID: 38813389 PMC: 11133575. DOI: 10.3389/fmed.2024.1365501.


Toward a common standard for data and specimen provenance in life sciences.

Wittner R, Holub P, Mascia C, Frexia F, Muller H, Plass M Learn Health Syst. 2024; 8(1):e10365.

PMID: 38249839 PMC: 10797572. DOI: 10.1002/lrh2.10365.


"Be sustainable": EOSC-Life recommendations for implementation of FAIR principles in life science data handling.

David R, Rybina A, Burel J, Heriche J, Audergon P, Boiten J EMBO J. 2023; 42(23):e115008.

PMID: 37964598 PMC: 10690449. DOI: 10.15252/embj.2023115008.

References
1.
Freedman L, Inglese J . The increasing urgency for standards in basic biologic research. Cancer Res. 2014; 74(15):4024-9. PMC: 4975040. DOI: 10.1158/0008-5472.CAN-14-0925. View

2.
Begley C, Ellis L . Drug development: Raise standards for preclinical cancer research. Nature. 2012; 483(7391):531-3. DOI: 10.1038/483531a. View

3.
Begley C, Ioannidis J . Reproducibility in science: improving the standard for basic and preclinical research. Circ Res. 2015; 116(1):116-26. DOI: 10.1161/CIRCRESAHA.114.303819. View

4.
Frexia F, Mascia C, Wittner R, Plass M, Muller H, Geiger J . The Common Provenance Model: Capturing Distributed Provenance in Life Sciences Processes. Stud Health Technol Inform. 2022; 294:415-416. DOI: 10.3233/SHTI220489. View

5.
Goode A, Gilbert B, Harkes J, Jukic D, Satyanarayanan M . OpenSlide: A vendor-neutral software foundation for digital pathology. J Pathol Inform. 2013; 4:27. PMC: 3815078. DOI: 10.4103/2153-3539.119005. View