Self-Propelled Initiative Collision at Microelectrodes with Vertically Mobile Micromotors

Overview

Journal Angew Chem Int Ed Engl

Specialty Chemistry

Date 2022 Aug 10

PMID 35946544

Authors

Ziyi Guo

Yanfang Wu

Zhouzun Xie

Junming Shao

Jian Liu

Yin Yao

Joseph Wang

Yansong Shen

J Justin Gooding

Kang Liang

Affiliations

Soon will be listed here.

Abstract

Impact experiments enable single particle analysis for many applications. However, the effect of the trajectory of a particle to an electrode on impact signals still requires further exploration. Here, we investigate the particle impact measurements versus motion using micromotors with controllable vertical motion. With biocatalytic cascade reactions, the micromotor system utilizes buoyancy as the driving force, thus enabling more regulated interactions with the electrode. With the aid of numerical simulations, the dynamic interactions between the electrode and micromotors are categorized into four representative patterns: approaching, departing, approaching-and-departing, and departing-and-reapproaching, which correspond well with the experimentally observed impact signals. This study offers a possibility of exploring the dynamic interactions between the electrode and particles, shedding light on the design of new electrochemical sensors.

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Self-Propelled Initiative Collision at Microelectrodes with Vertically Mobile Micromotors.

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References

Gooding J . Single Entity Electrochemistry Progresses to Cell Counting. Angew Chem Int Ed Engl. 2016; 55(42):12956-12958. DOI: 10.1002/anie.201606459. View

Baker L . Perspective and Prospectus on Single-Entity Electrochemistry. J Am Chem Soc. 2018; 140(46):15549-15559. PMC: 8720287. DOI: 10.1021/jacs.8b09747. View

Patrice F, Qiu K, Ying Y, Long Y . Single Nanoparticle Electrochemistry. Annu Rev Anal Chem (Palo Alto Calif). 2019; 12(1):347-370. DOI: 10.1146/annurev-anchem-061318-114902. View

Ma H, Chen J, Wang H, Hu P, Ma W, Long Y . Exploring dynamic interactions of single nanoparticles at interfaces for surface-confined electrochemical behavior and size measurement. Nat Commun. 2020; 11(1):2307. PMC: 7210955. DOI: 10.1038/s41467-020-16149-0. View

Nguyen T, Lee J, Kim H, Nam K, Kim B . Current research on single-entity electrochemistry for soft nanoparticle detection: Introduction to detection methods and applications. Biosens Bioelectron. 2020; 151:111999. DOI: 10.1016/j.bios.2019.111999. View

Liang K, Ricco R, Doherty C, Styles M, Bell S, Kirby N . Biomimetic mineralization of metal-organic frameworks as protective coatings for biomacromolecules. Nat Commun. 2015; 6:7240. PMC: 4468859. DOI: 10.1038/ncomms8240. View

Su H, Hurd Price C, Jing L, Tian Q, Liu J, Qian K . Janus particles: design, preparation, and biomedical applications. Mater Today Bio. 2020; 4:100033. PMC: 7061647. DOI: 10.1016/j.mtbio.2019.100033. View

Peng F, Tu Y, Wilson D . Micro/nanomotors towards in vivo application: cell, tissue and biofluid. Chem Soc Rev. 2017; 46(17):5289-5310. DOI: 10.1039/c6cs00885b. View

Kutorglo E, Elashnikov R, Rimpelova S, Ulbrich P, Ambrozova J, Svorcik V . Polypyrrole-Based Nanorobots Powered by Light and Glucose for Pollutant Degradation in Water. ACS Appl Mater Interfaces. 2021; 13(14):16173-16181. DOI: 10.1021/acsami.0c20055. View

10.

Abdelmohsen L, Nijemeisland M, Pawar G, Janssen G, Nolte R, van Hest J . Dynamic Loading and Unloading of Proteins in Polymeric Stomatocytes: Formation of an Enzyme-Loaded Supramolecular Nanomotor. ACS Nano. 2016; 10(2):2652-60. DOI: 10.1021/acsnano.5b07689. View

11.

Poon J, Batchelor-McAuley C, Tschulik K, Compton R . Single graphene nanoplatelets: capacitance, potential of zero charge and diffusion coefficient. Chem Sci. 2017; 6(5):2869-2876. PMC: 5490005. DOI: 10.1039/c5sc00623f. View

12.

Mun S, Lee S, Kim D, Kwon S . Various Current Responses of Single Silver Nanoparticle Collisions on a Gold Ultramicroelectrode Depending on the Collision Conditions. Chem Asian J. 2017; 12(18):2434-2440. DOI: 10.1002/asia.201700770. View

13.

Liang K, Richardson J, Cui J, Caruso F, Doonan C, Falcaro P . Metal-Organic Framework Coatings as Cytoprotective Exoskeletons for Living Cells. Adv Mater. 2016; 28(36):7910-7914. DOI: 10.1002/adma.201602335. View

14.

Guo Z, Liu J, Li Y, McDonald J, Zulkifli M, Khan S . Biocatalytic metal-organic framework nanomotors for active water decontamination. Chem Commun (Camb). 2020; 56(94):14837-14840. DOI: 10.1039/d0cc06429g. View

15.

Bouin J, Atallah M, Hultin H . The glucose oxidase--catalase system. Methods Enzymol. 1976; 44:478-88. DOI: 10.1016/s0076-6879(76)44034-x. View

16.

Parmar J, Vilela D, Villa K, Wang J, Sanchez S . Micro- and Nanomotors as Active Environmental Microcleaners and Sensors. J Am Chem Soc. 2018; 140(30):9317-9331. DOI: 10.1021/jacs.8b05762. View

17.

Peng Y, Huang H, Zhang Y, Kang C, Chen S, Song L . A versatile MOF-based trap for heavy metal ion capture and dispersion. Nat Commun. 2018; 9(1):187. PMC: 5768720. DOI: 10.1038/s41467-017-02600-2. View

18.

Patino T, Porchetta A, Jannasch A, Llado A, Stumpp T, Schaffer E . Self-Sensing Enzyme-Powered Micromotors Equipped with pH-Responsive DNA Nanoswitches. Nano Lett. 2019; 19(6):3440-3447. DOI: 10.1021/acs.nanolett.8b04794. View

19.

Chuah K, Wu Y, Vivekchand S, Gaus K, Reece P, Micolich A . Nanopore blockade sensors for ultrasensitive detection of proteins in complex biological samples. Nat Commun. 2019; 10(1):2109. PMC: 6506515. DOI: 10.1038/s41467-019-10147-7. View

20.

Pandey P, Garcia J, Guo J, Wang X, Yang D, He J . Differentiation of metallic and dielectric nanoparticles in solution by single-nanoparticle collision events at the nanoelectrode. Nanotechnology. 2019; 31(1):015503. DOI: 10.1088/1361-6528/ab4445. View