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Use of Chamomile Infusion to Mitigate Radiotherapy-Induced Dry Desquamation in Head and Neck Cancer Patients

Overview
Publisher Sage Publications
Specialties Oncology
Pharmacology
Date 2022 Jul 26
PMID 35880354
Authors
Affiliations
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Abstract

Purpose: To evaluate the effect of using a compress with infusion in the regression of dry desquamation and in the prevention of moist desquamation in head and neck cancer patients undergoing radiotherapy.

Methods: A prospective intervention study was carried out from May 2019 to May 2021. In total, 43 participants were included, who were instructed to apply the compress with the infusion 3 times a day, after occurrence of dry desquamation. Skin evaluation took place daily from initiation of the intervention up to the end of radiotherapy.

Results: All the participants presented dry desquamation regression, where 65.1% (95% CI 50.1-78.1) had total regression until the end of radiotherapy, with a mean of 9 days of regression. Only 34.9% (95% CI 21.8-49.9) of the participants developed moist desquamation by the end of the radiotherapy sessions, with a mean accumulated dose of ionizing radiation of 50.9 Gy.

Conclusion: This study highlighted the potential clinical benefits of using in the regression of dry desquamation and in the prevention of moist desquamation.

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