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How Microalgae is Effective in Oxygen Deficiency Aggravated Diseases? A Comprehensive Review of Literature

Overview
Publisher Dove Medical Press
Specialty Biotechnology
Date 2022 Jul 25
PMID 35874112
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Abstract

Hypoxia can aggravate the conditions of many oxygen-deficiency-aggravated diseases (ODAD), such as cancer, ischemic heart disease, and chronic wounds. Photosynthetic microalgae can alleviate the hepatotoxicity of the local microenvironment by producing oxygen. In addition, microalgae extracts have antitumor, anti-inflammatory, antibacterial, and antioxidant effects. These properties make them attractive candidates for developing methods to treat ODAD. Although researchers have exploited the advantages of microalgae and developed a variety of microalgae-based biomaterials to treat ODAD, a comprehensive review of this topic has not been presented previously. Therefore, in this review, we summarize the development and progress made in the field of developing microalgae-based biomaterials toward the treatment of ODAD. The challenges and prospects of this field are also discussed.

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References
1.
Cohen J, Goldstone A, Paulsen M, Shudo Y, Steele A, Edwards B . An innovative biologic system for photon-powered myocardium in the ischemic heart. Sci Adv. 2017; 3(6):e1603078. PMC: 5470824. DOI: 10.1126/sciadv.1603078. View

2.
Brown J, Wilson W . Exploiting tumour hypoxia in cancer treatment. Nat Rev Cancer. 2004; 4(6):437-47. DOI: 10.1038/nrc1367. View

3.
Bahramzadeh S, Tabarsa M, You S, Li C, Bita S . Purification, structural analysis and mechanism of murine macrophage cell activation by sulfated polysaccharides from Cystoseira indica. Carbohydr Polym. 2018; 205:261-270. DOI: 10.1016/j.carbpol.2018.10.022. View

4.
Bottone C, Camerlingo R, Miceli R, Salbitani G, Sessa G, Pirozzi G . Antioxidant and anti-proliferative properties of extracts from heterotrophic cultures of . Nat Prod Res. 2018; 33(11):1659-1663. DOI: 10.1080/14786419.2018.1425853. View

5.
Sinha B . Role of Oxygen and Nitrogen Radicals in the Mechanism of Anticancer Drug Cytotoxicity. J Cancer Sci Ther. 2020; 12(1):10-18. PMC: 7269165. View