SARS-ANI: a Global Open Access Dataset of Reported SARS-CoV-2 Events in Animals

Overview

Journal Sci Data

Specialty Science

Date 2022 Jul 23

PMID 35871228

Authors

Afra Nerpel

Liuhuaying Yang

Johannes Sorger

Annemarie Kasbohrer

Chris Walzer

Amelie Desvars-Larrive

Affiliations

Soon will be listed here.

Abstract

The zoonotic origin of SARS-CoV-2, the etiological agent of COVID-19, is not yet fully resolved. Although natural infections in animals are reported in a wide range of species, large knowledge and data gaps remain regarding SARS-CoV-2 in animal hosts. We used two major health databases to extract unstructured data and generated a global dataset of SARS-CoV-2 events in animals. The dataset presents harmonized host names, integrates relevant epidemiological and clinical data on each event, and is readily usable for analytical purposes. We also share the code for technical and visual validation of the data and created a user-friendly dashboard for data exploration. Data on SARS-CoV-2 occurrence in animals is critical to adapting monitoring strategies, preventing the formation of animal reservoirs, and tailoring future human and animal vaccination programs. The FAIRness and analytical flexibility of the data will support research efforts on SARS-CoV-2 at the human-animal-environment interface. We intend to update this dataset weekly for at least one year and, through collaborations, to develop it further and expand its use.

Citing Articles

Monitoring for respiratory viruses among wild canids, Texas.

Marushchak L, Pulscher L, Oguzie J, Silva D, Waldrup K, Watts D One Health. 2025; 20:100974.

PMID: 39898311 PMC: 11787532. DOI: 10.1016/j.onehlt.2025.100974.

Cross-Species Susceptibility of Emerging Variants of SARS-CoV-2 Spike.

Li M, Lv F, Li Z, Zhao C, Wang X, Zhu P Genes (Basel). 2024; 15(10).

PMID: 39457447 PMC: 11507407. DOI: 10.3390/genes15101321.

SARS-CoV-2 infection in brown-headed spider monkeys () at a wildlife rescue center on the coast of Ecuador-South America.

Carvajal M, Saenz C, Fuentes N, Guevara R, Munoz E, Prado-Vivar B Microbiol Spectr. 2024; 12(4):e0274123.

PMID: 38364080 PMC: 10986564. DOI: 10.1128/spectrum.02741-23.

Data on SARS-CoV-2 events in animals: Mind the gap!.

Nerpel A, Kasbohrer A, Walzer C, Desvars-Larrive A One Health. 2023; 17:100653.

PMID: 38024278 PMC: 10665207. DOI: 10.1016/j.onehlt.2023.100653.

Using drivers and transmission pathways to identify SARS-like coronavirus spillover risk hotspots.

Muylaert R, Wilkinson D, Kingston T, DOdorico P, Rulli M, Galli N Nat Commun. 2023; 14(1):6854.

PMID: 37891177 PMC: 10611769. DOI: 10.1038/s41467-023-42627-2.

References

Holmes E . COVID-19-lessons for zoonotic disease. Science. 2022; 375(6585):1114-1115. DOI: 10.1126/science.abn2222. View

Hale V, Dennis P, McBride D, Nolting J, Madden C, Huey D . SARS-CoV-2 infection in free-ranging white-tailed deer. Nature. 2021; 602(7897):481-486. PMC: 8857059. DOI: 10.1038/s41586-021-04353-x. View

Wilkinson M, Dumontier M, Aalbersberg I, Appleton G, Axton M, Baak A . The FAIR Guiding Principles for scientific data management and stewardship. Sci Data. 2016; 3:160018. PMC: 4792175. DOI: 10.1038/sdata.2016.18. View

Oreshkova N, Molenaar R, Vreman S, Harders F, Oude Munnink B, Hakze-van der Honing R . SARS-CoV-2 infection in farmed minks, the Netherlands, April and May 2020. Euro Surveill. 2020; 25(23). PMC: 7403642. DOI: 10.2807/1560-7917.ES.2020.25.23.2001005. View

Koopmans M . SARS-CoV-2 and the human-animal interface: outbreaks on mink farms. Lancet Infect Dis. 2020; 21(1):18-19. PMC: 7832374. DOI: 10.1016/S1473-3099(20)30912-9. View

Carlson C, Gibb R, Albery G, Brierley L, Connor R, Dallas T . The Global Virome in One Network (VIRION): an Atlas of Vertebrate-Virus Associations. mBio. 2022; 13(2):e0298521. PMC: 8941870. DOI: 10.1128/mbio.02985-21. View

McAloose D, Laverack M, Wang L, Killian M, Caserta L, Yuan F . From People to : Natural SARS-CoV-2 Infection in Tigers and Lions at the Bronx Zoo. mBio. 2020; 11(5). PMC: 7554670. DOI: 10.1128/mBio.02220-20. View

Mallapaty S . The search for animals harbouring coronavirus - and why it matters. Nature. 2021; 591(7848):26-28. DOI: 10.1038/d41586-021-00531-z. View

Zhang Q, Zhang H, Gao J, Huang K, Yang Y, Hui X . A serological survey of SARS-CoV-2 in cat in Wuhan. Emerg Microbes Infect. 2020; 9(1):2013-2019. PMC: 7534315. DOI: 10.1080/22221751.2020.1817796. View

10.

Frutos R, Devaux C . Mass culling of minks to protect the COVID-19 vaccines: is it rational?. New Microbes New Infect. 2020; 38:100816. PMC: 7670899. DOI: 10.1016/j.nmni.2020.100816. View

11.

Mahdy M, Younis W, Ewaida Z . An Overview of SARS-CoV-2 and Animal Infection. Front Vet Sci. 2020; 7:596391. PMC: 7759518. DOI: 10.3389/fvets.2020.596391. View

12.

Nerpel A, Yang L, Sorger J, Kasbohrer A, Walzer C, Desvars-Larrive A . SARS-ANI: a global open access dataset of reported SARS-CoV-2 events in animals. Sci Data. 2022; 9(1):438. PMC: 9308035. DOI: 10.1038/s41597-022-01543-8. View

13.

Miro G, Regidor-Cerrillo J, Checa R, Diezma-Diaz C, Montoya A, Garcia-Cantalejo J . SARS-CoV-2 Infection in One Cat and Three Dogs Living in COVID-19-Positive Households in Madrid, Spain. Front Vet Sci. 2021; 8:779341. PMC: 8660077. DOI: 10.3389/fvets.2021.779341. View

14.

Hamer S, Pauvolid-Correa A, Zecca I, Davila E, Auckland L, Roundy C . SARS-CoV-2 Infections and Viral Isolations among Serially Tested Cats and Dogs in Households with Infected Owners in Texas, USA. Viruses. 2021; 13(5). PMC: 8159091. DOI: 10.3390/v13050938. View

15.

Amuasi J, Walzer C, Heymann D, Carabin H, Huong L, Haines A . Calling for a COVID-19 One Health Research Coalition. Lancet. 2020; 395(10236):1543-1544. PMC: 7252094. DOI: 10.1016/S0140-6736(20)31028-X. View

16.

Oude Munnink B, Sikkema R, Nieuwenhuijse D, Molenaar R, Munger E, Molenkamp R . Transmission of SARS-CoV-2 on mink farms between humans and mink and back to humans. Science. 2020; 371(6525):172-177. PMC: 7857398. DOI: 10.1126/science.abe5901. View

17.

Chandler J, Bevins S, Ellis J, Linder T, Tell R, Jenkins-Moore M . SARS-CoV-2 exposure in wild white-tailed deer (). Proc Natl Acad Sci U S A. 2021; 118(47). PMC: 8617405. DOI: 10.1073/pnas.2114828118. View

18.

Schoch C, Ciufo S, Domrachev M, Hotton C, Kannan S, Khovanskaya R . NCBI Taxonomy: a comprehensive update on curation, resources and tools. Database (Oxford). 2020; 2020. PMC: 7408187. DOI: 10.1093/database/baaa062. View

19.

Molloy J . The Open Knowledge Foundation: open data means better science. PLoS Biol. 2011; 9(12):e1001195. PMC: 3232214. DOI: 10.1371/journal.pbio.1001195. View

20.

Sit T, Brackman C, Ip S, Tam K, Law P, To E . Infection of dogs with SARS-CoV-2. Nature. 2020; 586(7831):776-778. PMC: 7606701. DOI: 10.1038/s41586-020-2334-5. View