Carcinosarcoma with Chondroid Differentiation and Neuroendocrine Carcinoma: Unusual Triphasic Tumour Arising from Intracholecystic Papillary Neoplasm of the Gall Bladder

Overview

Journal BMJ Case Rep

Specialty General Medicine

Date 2022 Jul 20

PMID 35858746

Authors

Smitha Mruthyunjayappa

Chirag Rasiklal Patel

Sushanth Reddy

Sameer Al Diffalha

Affiliations

Soon will be listed here.

Abstract

Herein, we report a man in his 70s with gallbladder mass. Microscopically, the tumour demonstrated moderately differentiated adenocarcinoma, sarcoma with focal chondroid differentiation and high-grade neuroendocrine tumour component arising in an intracholecystic papillary neoplasm. The patient did not receive adjuvant chemotherapy in the setting of complete surgical resection. Patient presented with extensive metastasis after 47 months and died 3 months later. Due to the low incidence and poor prognosis of this tumour, it is essential to gather all the individual experience-based information. To our knowledge, this is the first reported case of carcinosarcoma arising from intracholecystic papillary-tubular neoplasm.

Citing Articles

Extensively Invasive Gallbladder Cancer from Intracholecystic Papillary Neoplasm Treated with Pylorus-Preserving Pancreaticoduodenectomy and Extended Cholecystectomy: A Case Report and Literature Review.

Kumagai H, Umemura A, Nitta H, Katagiri H, Nishiya M, Uesugi N Case Rep Surg. 2023; 2023:5825045.

PMID: 37396494 PMC: 10314817. DOI: 10.1155/2023/5825045.

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