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» Articles » PMID: 35857789

Expanding the Epitranscriptome: Dihydrouridine in MRNA

Overview
Journal PLoS Biol
Specialty Biology
Date 2022 Jul 20
PMID 35857789
Authors
Sameer Dixit
Samie R Jaffrey
Affiliations
Soon will be listed here.
Abstract

Nucleotide modifications can markedly influence mRNA processing and metabolism. New studies, one in PLOS Biology, show that approximately 130 yeast mRNAs contain dihydrouridine, a derivative of uridine. Functional studies show that dihydrouridine, in some cases, can affect mRNA splicing.

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