High-Frequency Ultrasound Elastography to Assess the Nonlinear Elastic Properties of the Cornea and Ciliary Body

Overview

Journal IEEE Trans Ultrason Ferroelectr Freq Control

Specialties Biomedical Engineering
Nuclear Medicine

Date 2022 Jul 12

PMID 35820015

Authors

Junhang Zhang

Javier Murgoitio-Esandi

Xuejun Qian

Runze Li

Chen Gong

Amir Nankali

Liang Hao

Benjamin Y Xu

K Kirk Shung

Assad Oberai

Qifa Zhou

Affiliations

Soon will be listed here.

Abstract

Mechanical properties of the anterior anatomical structures of the eye, such as the cornea and ciliary body, play a key role in the ocular function and homeostasis. However, measuring the biomechanical properties of the anterior ocular structures, especially deeper structures, such as the ciliary body, remains a challenge due to the lack of high-resolution imaging tools. Herein, we implement a mechanical shaker-based high-frequency ultrasound elastography technique that can track the induced elastic wave propagation to assess the linear and nonlinear elastic properties of anterior ocular structures. The findings of this study advance our understanding of the role of anterior ocular structures in the pathogenesis of different ocular disorders, such as glaucoma.

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