Changes of Intestinal Microbiota and Microbiota-based Treatments in IBD

Overview

Journal Arch Microbiol

Specialty Microbiology

Date 2022 Jul 1

PMID 35776212

Authors

Qianyu Li

Siyu Zhou

Yanna Wang

Jing Cong

Affiliations

Soon will be listed here.

Abstract

Inflammatory bowel disease (IBD) has gained increasing attention from researchers in terms of its pathophysiology as a global disease with a growing incidence. Although the exact etiology of IBD is still unknown currently, various studies have made us realize that it is related to the dysbiosis of intestinal microbiota and the link between the two may not just be a simple causal relationship, but also a dynamic and complicated one. The intestinal microbiota has been confirmed to be closely related to the occurrence, development, and treatment of IBD. Therefore, this review focuses on the changes in the structure, function, and metabolites of intestinal bacteria, fungi, and viruses in influencing IBD, as well as various approaches to IBD treatment by changing disordered intestinal microbiota. Ultimately, more clinical studies will be needed to focus on the efficacy of intestinal microbiota-based treatments in IBD, because of the existence of both advantages and disadvantages.

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