Sulfur-Containing Compounds from Endophytic Fungi: Sources, Structures and Bioactivities

Overview

Journal J Fungi (Basel)

Date 2022 Jun 23

PMID 35736111

Authors

Yaqin Fan

Zhiheng Ma

Yan Zhang

Yufei Wang

Yousong Ding

Cong Wang

Shugeng Cao

Affiliations

Soon will be listed here.

Abstract

Endophytic fungi have attracted increasing attention as an under-explored source for the discovery and development of structurally and functionally diverse secondary metabolites. These microorganisms colonize their hosts, primarily plants, and demonstrate diverse ecological distribution. Among endophytic fungal natural products, sulfur-containing compounds feature one or more sulfur atoms and possess a range of bioactivities, e.g., cytotoxicity and antimicrobial activities. These natural products mainly belong to the classes of polyketides, nonribosomal peptides, terpenoids, and hybrids. Here, we reviewed the fungal producers, plant sources, chemical structures, and bioactivities of 143 new sulfur-containing compounds that were reported from 1985 to March 2022.

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