The Role of Genetics, Epigenetics, and the Environment in ASD: A Mini Review

Overview

Journal Epigenomes

Date 2022 Jun 23

PMID 35735472

Authors

Asim A Khogeer

Iman S AboMansour

Dia A Mohammed

Affiliations

Soon will be listed here.

Abstract

According to recent findings, variances in autism spectrum disorder (ASD) risk factors might be determined by several factors, including molecular genetic variants. Accumulated evidence has also revealed the important role of biological and chemical pathways in ASD aetiology. In this paper, we assess several reviews with regard to their quality of evidence and provide a brief outline of the presumed mechanisms of the genetic, epigenetic, and environmental risk factors of ASD. We also review some of the critical literature, which supports the basis of each factor in the underlying and specific risk patterns of ASD. Finally, we consider some of the implications of recent research regarding potential molecular targets for future investigations.

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