Nucleotide Sequence Sharing Between the Human Genome and Primers for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Detection

Overview

Journal Glob Med Genet

Publisher Thieme

Date 2022 Jun 16

PMID 35707780

Authors

Darja Kanduc

Affiliations

Soon will be listed here.

Abstract

This study shows that oligonucleotide sequences are shared between the human genome and primers that have been proposed/used for SARS-CoV-2 detection by polymerase chain reaction (PCR). The high level of sharing (namely, up to 19mer with a maximum number of gaps equal to 2) might bear implications for the diagnostic validity of SARS-CoV-2 detection by PCR.

Citing Articles

SARS-CoV-2: The Self-Nonself Issue and Diagnostic Tests.

Kanduc D J Lab Physicians. 2023; 15(1):56-61.

PMID: 37064977 PMC: 10104719. DOI: 10.1055/s-0042-1750078.

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