» Articles » PMID: 32171952

The SARS-CoV-2 Outbreak: What We Know

Overview
Publisher Elsevier
Date 2020 Mar 16
PMID 32171952
Citations 509
Authors
Affiliations
Soon will be listed here.
Abstract

There is a current worldwide outbreak of the novel coronavirus Covid-19 (coronavirus disease 2019; the pathogen called SARS-CoV-2; previously 2019-nCoV), which originated from Wuhan in China and has now spread to 6 continents including 66 countries, as of 24:00 on March 2, 2020. Governments are under increased pressure to stop the outbreak from spiraling into a global health emergency. At this stage, preparedness, transparency, and sharing of information are crucial to risk assessments and beginning outbreak control activities. This information should include reports from outbreak site and from laboratories supporting the investigation. This paper aggregates and consolidates the epidemiology, clinical manifestations, diagnosis, treatments and preventions of this new type of coronavirus.

Citing Articles

The Impact of COVID-19 on Dental Clinic Transmission: Leveraging Internet of Things Technology.

Uygun-Can B, Durmazpinar P, Hatipoglu S, Acar-Bolat B, Ozen C, Sazak-Ovecoglu H J Multidiscip Healthc. 2025; 18:1319-1334.

PMID: 40060992 PMC: 11889996. DOI: 10.2147/JMDH.S499841.


SARS-CoV-2 XEC: A Genome-Based Survey.

Scarpa F, Branda F, Ceccarelli G, Romano C, Locci C, Pascale N Microorganisms. 2025; 13(2).

PMID: 40005620 PMC: 11857677. DOI: 10.3390/microorganisms13020253.


Beneficial effects and possible mechanism of intake coffee for COVID-19: A meta-analysis and molecular docking.

Fan Y, Duan Y, Zhang A, Wang Y Medicine (Baltimore). 2025; 104(7):e41550.

PMID: 39960901 PMC: 11835096. DOI: 10.1097/MD.0000000000041550.


Carboxylated Graphene: An Innovative Approach to Enhanced IgA-SARS-CoV-2 Electrochemical Biosensing.

de Souza Freire L, Gandarilla A, Barcelay Y, Ruzo C, Salgado B, Tavares A Biosensors (Basel). 2025; 15(1).

PMID: 39852085 PMC: 11764328. DOI: 10.3390/bios15010034.


Enhancing RT-PCR Throughput and Sensitivity through Large-Scale Sample Pooling Using a Nano-Hybrid Membrane.

Lee N, Kim K, Hong J, Lee S, Park J, Lee D Adv Sci (Weinh). 2025; 12(10):e2408771.

PMID: 39834032 PMC: 11904979. DOI: 10.1002/advs.202408771.


References
1.
Li Q, Guan X, Wu P, Wang X, Zhou L, Tong Y . Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-Infected Pneumonia. N Engl J Med. 2020; 382(13):1199-1207. PMC: 7121484. DOI: 10.1056/NEJMoa2001316. View

2.
Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J . Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China. JAMA. 2020; 323(11):1061-1069. PMC: 7042881. DOI: 10.1001/jama.2020.1585. View

3.
Guan W, Ni Z, Hu Y, Liang W, Ou C, He J . Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med. 2020; 382(18):1708-1720. PMC: 7092819. DOI: 10.1056/NEJMoa2002032. View

4.
Das K, Lee E, Al Jawder S, Enani M, Singh R, Skakni L . Acute Middle East Respiratory Syndrome Coronavirus: Temporal Lung Changes Observed on the Chest Radiographs of 55 Patients. AJR Am J Roentgenol. 2015; 205(3):W267-74. DOI: 10.2214/AJR.15.14445. View

5.
Holshue M, DeBolt C, Lindquist S, Lofy K, Wiesman J, Bruce H . First Case of 2019 Novel Coronavirus in the United States. N Engl J Med. 2020; 382(10):929-936. PMC: 7092802. DOI: 10.1056/NEJMoa2001191. View