Saliva Diagnostics

Overview

Journal Annu Rev Anal Chem (Palo Alto Calif)

Publisher Annual Reviews

Specialty Chemistry

Date 2022 Jun 13

PMID 35696523

Authors

Taichiro Nonaka

David T W Wong

Affiliations

Soon will be listed here.

Abstract

Cancer remains one of the leading causes of death, and early detection of this disease is crucial for increasing survival rates. Although cancer can be diagnosed following tissue biopsy, the biopsy procedure is invasive; liquid biopsy provides an alternative that is more comfortable for the patient. While blood, urine, and cerebral spinal fluid can all be used as a source of liquid biopsy, saliva is an ideal source of body fluid that is readily available and easily collected in the most noninvasive manner. Characterization of salivary constituents in the disease setting provides critical data for understanding pathophysiology and the evaluation of diagnostic potential. The aim of saliva diagnostics is therefore to develop a rapid and noninvasive detection of oral and systemic diseases that could be used together with compact analysis systems in the clinic to facilitate point-of-care diagnostics.

Citing Articles

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Saliva as a Diagnostic Tool for Systemic Diseases-A Narrative Review.

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