Comparison of Effects of Ingested Medium- and Long-chain Triglyceride on Gallbladder Volume and Release of Cholecystokinin and Other Gut Peptides

Overview

Journal Dig Dis Sci

Specialty Gastroenterology

Date 1987 May 1

PMID 3568934

Citations 15

Authors

P E Isaacs

S Ladas

I C Forgacs

R H Dowling

S V Ellam

T E Adrian

S R Bloom

Affiliations

Soon will be listed here.

Abstract

In a double-blind, crossover study of the effect of ingested medium-chain triglyceride (MCT) and long-chain triglyceride (LCT) in six normal subjects, the gallbladder did not contract after ingestion of MCT but instead had significantly increased in volume at 2 hr after the meal. Plasma cholecystokinin (CCK) increased after the MCT meal, but gastrin, motilin, pancreatic polypeptide (PP), and GIP were unaffected. The long-chain triglyceride meal evoked a brisk and sustained gallbladder contraction, higher levels of CCK, and a significant increase in plasma PP and GIP levels.

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