The Feasibility and User-Experience of a Digital Health Intervention Designed to Prevent Weight Gain in New Kidney Transplant Recipients-The ExeRTiOn2 Trial

Overview

Journal Front Nutr

Specialty Nutritional Sciences

Date 2022 Jun 9

PMID 35677553

Authors

Ellen M Castle

Giulia Dijk

Elham Asgari

Sapna Shah

Rachel Phillips

James Greenwood

Kate Bramham

Joseph Chilcot

Sharlene A Greenwood

Affiliations

Soon will be listed here.

Abstract

Clinical Trial Registration: www.clinicalTrials.gov, identifier: NCT03996551.

Citing Articles

Depression and anxiety in people with kidney disease: understanding symptom variability, patient experience and preferences for mental health support.

Chilcot J, Pearce C, Hall N, Rehman Z, Norton S, Griffiths S J Nephrol. 2025; .

PMID: 39799543 DOI: 10.1007/s40620-024-02194-1.

Digital Physical Activity and Exercise Interventions for People Living with Chronic Kidney Disease: A Systematic Review of Health Outcomes and Feasibility.

Letton M, Trn T, Flower S, Wewege M, Wang A, Sandler C J Med Syst. 2024; 48(1):63.

PMID: 38951385 PMC: 11217122. DOI: 10.1007/s10916-024-02081-z.

Patients' acceptability of self-selected digital health services to support diet and exercise among people with complex chronic conditions: Mixed methods study.

Barnett A, Catapan S, Jegatheesan D, Conley M, Keating S, Mayr H Digit Health. 2024; 10:20552076241245278.

PMID: 38854917 PMC: 11162125. DOI: 10.1177/20552076241245278.

Preferences of people with chronic kidney disease regarding digital health interventions that promote healthy lifestyle: qualitative systematic review with meta-ethnography.

Trn T, Ambrens M, Nguyn J, Coleman E, Gilanyi Y, Letton M BMJ Open. 2024; 14(5):e082345.

PMID: 38802278 PMC: 11131123. DOI: 10.1136/bmjopen-2023-082345.

Lifestyle interventions delivered by eHealth in chronic kidney disease: A scoping review.

Curtis F, Burton J, Butt A, Dhaliwal H, Graham-Brown M, Lightfoot C PLoS One. 2024; 19(1):e0297107.

PMID: 38266006 PMC: 10807786. DOI: 10.1371/journal.pone.0297107.

References

Ryan D, Yockey S . Weight Loss and Improvement in Comorbidity: Differences at 5%, 10%, 15%, and Over. Curr Obes Rep. 2017; 6(2):187-194. PMC: 5497590. DOI: 10.1007/s13679-017-0262-y. View

Cleemput I, Kesteloot K, Moons P, Vanrenterghem Y, van Hooff J, Squifflet J . The construct and concurrent validity of the EQ-5D in a renal transplant population. Value Health. 2004; 7(4):499-509. DOI: 10.1111/j.1524-4733.2004.74013.x. View

Williamson D, Bray G, Ryan D . Is 5% weight loss a satisfactory criterion to define clinically significant weight loss?. Obesity (Silver Spring). 2015; 23(12):2319-20. DOI: 10.1002/oby.21358. View

Kostakis I, Kassimatis T, Bianchi V, Paraskeva P, Flach C, Callaghan C . UK renal transplant outcomes in low and high BMI recipients: the need for a national policy. J Nephrol. 2019; 33(2):371-381. DOI: 10.1007/s40620-019-00654-7. View

Cashion A, Hathaway D, Stanfill A, Thomas F, Ziebarth J, Cui Y . Pre-transplant predictors of one yr weight gain after kidney transplantation. Clin Transplant. 2014; 28(11):1271-8. PMC: 4576829. DOI: 10.1111/ctr.12456. View

Kohl L, Signori L, Ribeiro R, Silva A, Moreira P, Dipp T . Prognostic value of the six-minute walk test in end-stage renal disease life expectancy: a prospective cohort study. Clinics (Sao Paulo). 2012; 67(6):581-6. PMC: 3370308. DOI: 10.6061/clinics/2012(06)06. View

Little P, Stuart B, Hobbs F, Kelly J, Smith E, Bradbury K . An internet-based intervention with brief nurse support to manage obesity in primary care (POWeR+): a pragmatic, parallel-group, randomised controlled trial. Lancet Diabetes Endocrinol. 2016; 4(10):821-8. DOI: 10.1016/S2213-8587(16)30099-7. View

Wise R, Brown C . Minimal clinically important differences in the six-minute walk test and the incremental shuttle walking test. COPD. 2006; 2(1):125-9. DOI: 10.1081/copd-200050527. View

Harper L, Morgan M, Chanouzas D, Caulfield H, Coughlan L, Dean C . Treatment of fatigue with physical activity and behavioural change support in vasculitis: study protocol for an open-label randomised controlled feasibility study. BMJ Open. 2018; 8(10):e023769. PMC: 6224747. DOI: 10.1136/bmjopen-2018-023769. View

10.

. KDIGO clinical practice guideline for the care of kidney transplant recipients. Am J Transplant. 2009; 9 Suppl 3:S1-155. DOI: 10.1111/j.1600-6143.2009.02834.x. View

11.

Schmid-Mohler G, Zala P, Graf N, Witschi P, Mueller T, Wuthrich R . Comparison of a Behavioral Versus an Educational Weight Management Intervention After Renal Transplantation: A Randomized Controlled Trial. Transplant Direct. 2020; 5(12):e507. PMC: 7004588. DOI: 10.1097/TXD.0000000000000936. View

12.

Glicklich D, Mustafa M . Obesity in Kidney Transplantation: Impact on Transplant Candidates, Recipients, and Donors. Cardiol Rev. 2018; 27(2):63-72. DOI: 10.1097/CRD.0000000000000216. View

13.

Chan W, Bosch J, Jones D, McTernan P, Phillips A, Borrows R . Obesity in kidney transplantation. J Ren Nutr. 2013; 24(1):1-12. DOI: 10.1053/j.jrn.2013.09.002. View

14.

Cook S, MacLaughlin H, Macdougall I . A structured weight management programme can achieve improved functional ability and significant weight loss in obese patients with chronic kidney disease. Nephrol Dial Transplant. 2007; 23(1):263-8. DOI: 10.1093/ndt/gfm511. View

15.

Bradbury K, Dennison L, Little P, Yardley L . Using mixed methods to develop and evaluate an online weight management intervention. Br J Health Psychol. 2014; 20(1):45-55. DOI: 10.1111/bjhp.12125. View

16.

MacLaughlin H, Cook S, Kariyawasam D, Roseke M, van Niekerk M, Macdougall I . Nonrandomized trial of weight loss with orlistat, nutrition education, diet, and exercise in obese patients with CKD: 2-year follow-up. Am J Kidney Dis. 2009; 55(1):69-76. DOI: 10.1053/j.ajkd.2009.09.011. View

17.

Koufaki P, Greenwood S, Macdougall I, Mercer T . Exercise therapy in individuals with chronic kidney disease: a systematic review and synthesis of the research evidence. Annu Rev Nurs Res. 2014; 31:235-75. DOI: 10.1891/0739-6686.31.235. View

18.

Winters G, Kendall T, Radio S, Wilson J, Switzer B, Remmenga J . Posttransplant obesity and hyperlipidemia: major predictors of severity of coronary arteriopathy in failed human heart allografts. J Heart Transplant. 1990; 9(4):364-71. View

19.

Bandura A . Self-efficacy: toward a unifying theory of behavioral change. Psychol Rev. 1977; 84(2):191-215. DOI: 10.1037//0033-295x.84.2.191. View

20.

Stauss M, Floyd L, Becker S, Ponnusamy A, Woywodt A . Opportunities in the cloud or pie in the sky? Current status and future perspectives of telemedicine in nephrology. Clin Kidney J. 2021; 14(2):492-506. PMC: 7454484. DOI: 10.1093/ckj/sfaa103. View