» Articles » PMID: 35675403

Chromatographic Separation of Active Polymer-like Worm Mixtures by Contour Length and Activity

Overview
Journal Sci Adv
Specialties Biology
Science
Date 2022 Jun 8
PMID 35675403
Authors
Affiliations
Soon will be listed here.
Abstract

The convective transport rate of polymers through confined geometries depends on their size, allowing for size-based separation of polymer mixtures (chromatography). Here, we investigate whether mixtures of active polymers can be separated in a similar manner based on their activity. We use thin, living worms as a model system for active polymers and study the transport of these worms by an imposed flow through a channel filled with a hexagonal pillar array. The transport rate through the channel depends strongly on the degree of activity, an effect that we assign to the different distribution of conformations sampled by the worms depending on their activity. Our results demonstrate a unique way to sort mixtures of active polymers based on their activity and provide a versatile and convenient experimental system to investigate the hydrodynamics of active polymers.

Citing Articles

Worm blobs as entangled living polymers: from topological active matter to flexible soft robot collectives.

Deblais A, Prathyusha K, Sinaasappel R, Tuazon H, Tiwari I, Patil V Soft Matter. 2023; 19(37):7057-7069.

PMID: 37706563 PMC: 10523214. DOI: 10.1039/d3sm00542a.


Ultrafast reversible self-assembly of living tangled matter.

Patil V, Tuazon H, Kaufman E, Chakrabortty T, Qin D, Dunkel J Science. 2023; 380(6643):392-398.

PMID: 37104611 PMC: 11194538. DOI: 10.1126/science.ade7759.

References
1.
Loisy A, Eggers J, Liverpool T . Active Suspensions have Nonmonotonic Flow Curves and Multiple Mechanical Equilibria. Phys Rev Lett. 2018; 121(1):018001. DOI: 10.1103/PhysRevLett.121.018001. View

2.
Deblais A, Maggs A, Bonn D, Woutersen S . Phase Separation by Entanglement of Active Polymerlike Worms. Phys Rev Lett. 2020; 124(20):208006. DOI: 10.1103/PhysRevLett.124.208006. View

3.
Winkler R, Gompper G . The physics of active polymers and filaments. J Chem Phys. 2020; 153(4):040901. DOI: 10.1063/5.0011466. View

4.
Martin-Gomez A, Gompper G, Winkler R . Active Brownian Filamentous Polymers under Shear Flow. Polymers (Basel). 2019; 10(8). PMC: 6403868. DOI: 10.3390/polym10080837. View

5.
Ostapenko T, Schwarzendahl F, Boddeker T, Kreis C, Cammann J, Mazza M . Curvature-Guided Motility of Microalgae in Geometric Confinement. Phys Rev Lett. 2018; 120(6):068002. DOI: 10.1103/PhysRevLett.120.068002. View