Effectiveness of Glass Ionomer Cements in the Restorative Treatment of Radiation-related Caries - a Systematic Review
Overview
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Purpose: The aim of this systematic review was to investigate the clinical effectiveness of glass ionomer cements (GICs) compared to other restorative materials in the treatment of radiation-related caries.
Methods: Two independent researchers searched literature databases (PubMed, Scopus, Web of Science, Cochrane Library, Lilacs/BBO) and the grey literature to identify clinical trials that compared GICs with other restorative materials for the treatment of radiation-related caries. The clinical criteria considered for the performance of the restorations were based on the parameters of marginal adaptation/anatomical form, secondary caries, retention, and cumulative failures of the restorations. The methodological quality and risk of bias were evaluated using the Cochrane Collaboration tool.
Results: From a total of 511, only four articles fulfilled the inclusion criteria. Conventional GIC restorations presented higher marginal adaptation failures than the resin-modified glass ionomer cements (RM-GICs) and composite restorations in all of the follow-up periods. Secondary caries was not observed in conventional GIC restorations throughout the follow-up periods, in three out of four of the included studies. RM-GICs and composite restorations showed significantly lower cumulative failure rates than conventional GICs at 6-, 12-, and 18-month follow-ups.
Conclusion: Due to insufficient scientific evidence, it was not possible to conclude that GICs are more effective than other restorative materials for the treatment of radiation-related caries.
Sitaram S, Paulraj J, Maiti S, Shanmugam R Int J Clin Pediatr Dent. 2025; 17(11):1229-1235.
PMID: 39781388 PMC: 11703768. DOI: 10.5005/jp-journals-10005-2984.
Retrospective Clinical Evaluation of RMGIC/GIC Class V Restorations.
Santos M, Leon L, Siddique I, Butler S Dent J (Basel). 2023; 11(9).
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Eggmann F, Hwang J, Ayub J, Mante F Materials (Basel). 2023; 16(7).
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Fierascu R Nanomaterials (Basel). 2022; 12(21).
PMID: 36364603 PMC: 9658828. DOI: 10.3390/nano12213827.