» Articles » PMID: 35654492

Comparison of the Utility of High-Resolution CT-DWI and T2WI-DWI Fusion Images for the Localization of Cholesteatoma

Overview
Specialty Neurology
Date 2022 Jun 2
PMID 35654492
Authors
Affiliations
Soon will be listed here.
Abstract

Background And Purpose: Cholesteatoma is an aggressive disease that may lead to hearing impairment. This study aimed to compare the utility of high-resolution CT and TSE-DWI fusion images with that of T2WI and TSE-DWI fusion images in the localization of middle ear cholesteatoma.

Materials And Methods: Seventy-one patients with middle ear cholesteatoma were retrospectively recruited. High-resolution CT, T2WI with fat suppression, and TSE-DWI scans were obtained, and image fusion was performed using a 3D reconstruction postprocessing workstation to form CT-DWI and T2WI-DWI fusion images. The quality of the 2 fused images was subjectively evaluated using a 5-point Likert scale with the horizontal semicircular canal transverse position as the reference. Receiver operating characteristic analysis was performed, and the diagnostic efficacies of CT-DWI and T2WI-DWI fusion images in localizing middle ear cholesteatoma were calculated.

Results: The overall quality of T2WI-DWI fusion images was slightly higher than that of CT-DWI fusion images (< .001), and the semicircular canal was slightly less clear on T2WI-DWI than on CT-DWI (< .001). No statistical difference was found in the diagnostic confidence between them. In the localization of middle ear cholesteatoma, the accuracy, sensitivity, and specificity of T2WI-DWI fusion images and CT-DWI fusion images were equivalent for involvement of the attic, tympanic cavity, mastoid antrum, and mastoid process, with no statistically significant differences.

Conclusions: T2WI-DWI fusion images could replace CT-DWI in the preoperative selection of surgical options for middle ear cholesteatoma.

References
1.
Alzahrani M, Alhazmi R, Belair M, Saliba I . Postoperative diffusion weighted MRI and preoperative CT scan fusion for residual cholesteatoma localization. Int J Pediatr Otorhinolaryngol. 2016; 90:259-263. DOI: 10.1016/j.ijporl.2016.09.034. View

2.
Tolisano A, Killeen D, Hunter J, Kutz Jr J, Isaacson B . The Antrum-Malleus-Tegmen Score: A Pilot Study Assessing Preoperative Radiographic Predictors for Transcanal Endoscopic Cholesteatoma Dissection. Otol Neurotol. 2019; 40(9):e901-e908. DOI: 10.1097/MAO.0000000000002354. View

3.
Anschuetz L, Presutti L, Marchioni D, Bonali M, Wimmer W, Villari D . Discovering Middle Ear Anatomy by Transcanal Endoscopic Ear Surgery: A Dissection Manual. J Vis Exp. 2018; (131). PMC: 5908483. DOI: 10.3791/56390. View

4.
Lingam R, Bassett P . A Meta-Analysis on the Diagnostic Performance of Non-Echoplanar Diffusion-Weighted Imaging in Detecting Middle Ear Cholesteatoma: 10 Years On. Otol Neurotol. 2017; 38(4):521-528. DOI: 10.1097/MAO.0000000000001353. View

5.
Yamashita K, Hiwatashi A, Togao O, Kikuchi K, Matsumoto N, Obara M . High-resolution three-dimensional diffusion-weighted MRI/CT image data fusion for cholesteatoma surgical planning: a feasibility study. Eur Arch Otorhinolaryngol. 2014; 272(12):3821-4. DOI: 10.1007/s00405-014-3467-7. View