» Articles » PMID: 35614977

Consumption of Food Components of the Mediterranean Diet Decreases the Risk of Breast Cancer in the Makkah Region, Saudi Arabia: A Case-Control Study

Abstract

Background: Breast cancer is one of the leading causes of death worldwide, it affects both men and women. In Saudi Arabia, breast cancer has been the most prevalent type of cancer in women, for the past few years. Dietary habits and cultural beliefs vary according to region, and further studies are required to demonstrate the relationship between these dietary habits and cultural beliefs and the risk of developing breast cancer. This study is aimed to discover the relationship between preventive dietary factors of the Mediterranean diet and rates of breast cancer among postmenopausal women in the Makkah region of Saudi Arabia.

Methods: A case-control study was conducted in King Abdulla Medical City Hospital, Makkah, Saudi Arabia and included 432 Saudi female participants: 218 in the control group and 214 breast cancer patients. All participants were postmenopausal, around the same age, and all were ethnically Arab Saudis. Data were obtained using a self-administered validated questionnaire.

Results: Study results showed that a diet that includes 1-2 servings of legumes weekly, 1-5 servings of fish weekly, 1-5 servings of dairy products daily, 3-5 servings of fruits and vegetables daily, and more than one cup of black tea and coffee per day significantly ( < 0.05) reduces the risk of breast cancer.

Conclusion: This study demonstrates that consuming a Mediterranean diet, which includes legumes, fish, fruits and vegetables, black tea, coffee, and low intake of dairy products, works as a preventive factor against breast cancer in postmenopausal females from the Makkah region.

Citing Articles

Associations Between Dietary Factors and Breast Cancer Risk: A Systematic Review of Evidence from the MENA Region.

Lamchabbek N, Elattabi C, Bour A, Chimera B, Boutayeb S, Belyamani L Nutrients. 2025; 17(3).

PMID: 39940252 PMC: 11820300. DOI: 10.3390/nu17030394.


Effects of Religious Fasting on Markers of Oxidative Status in Vitamin D-Deficient and Overweight Orthodox Nuns versus Implementation of Time-Restricted Eating in Lay Women from Central and Northern Greece.

Karras S, Michalakis K, Tekos F, Skaperda Z, Vardakas P, Ziakas P Nutrients. 2024; 16(19).

PMID: 39408266 PMC: 11478604. DOI: 10.3390/nu16193300.


Turkish coffee has an antitumor effect on breast cancer cells in vitro and in vivo.

Amin M, Abdelmohsen U, Samra Y Nutr Metab (Lond). 2024; 21(1):73.

PMID: 39272080 PMC: 11396339. DOI: 10.1186/s12986-024-00846-4.


The Impact of Dietary Unsaturated Fat or the Mediterranean Diet on Women Diagnosed With Breast Cancer: A Systematic Review.

Virani S, Afreen S, Perthiani A, Sangster E, Lanka N, Acharya P Cureus. 2024; 16(7):e65362.

PMID: 39184716 PMC: 11344571. DOI: 10.7759/cureus.65362.


Dietary Patterns Associated with Breast Cancer in the Middle East: A Scoping Review.

Zamzam S, Said S, Yaghi J, Faisal F, Hassan D, Abdul Majeed S Nutrients. 2024; 16(5).

PMID: 38474708 PMC: 10934189. DOI: 10.3390/nu16050579.


References
1.
McCann S, Ip C, Ip M, McGuire M, Muti P, Edge S . Dietary intake of conjugated linoleic acids and risk of premenopausal and postmenopausal breast cancer, Western New York Exposures and Breast Cancer Study (WEB Study). Cancer Epidemiol Biomarkers Prev. 2004; 13(9):1480-4. View

2.
Chen L, Li M, Li H . Milk and yogurt intake and breast cancer risk: A meta-analysis. Medicine (Baltimore). 2019; 98(12):e14900. PMC: 6709252. DOI: 10.1097/MD.0000000000014900. View

3.
Naja F, Nasreddine L, Awada S, Ahmad R, Hwalla N . Nutrition in the Prevention of Breast Cancer: A Middle Eastern Perspective. Front Public Health. 2019; 7:316. PMC: 6856137. DOI: 10.3389/fpubh.2019.00316. View

4.
Al-Ansari M, Aboussekhra A . Caffeine mediates sustained inactivation of breast cancer-associated myofibroblasts via up-regulation of tumor suppressor genes. PLoS One. 2014; 9(3):e90907. PMC: 3940951. DOI: 10.1371/journal.pone.0090907. View

5.
den Hartigh L . Conjugated Linoleic Acid Effects on Cancer, Obesity, and Atherosclerosis: A Review of Pre-Clinical and Human Trials with Current Perspectives. Nutrients. 2019; 11(2). PMC: 6413010. DOI: 10.3390/nu11020370. View