The Modified COVID-19 Yorkshire Rehabilitation Scale (C19-YRSm) Patient-reported Outcome Measure for Long Covid or Post-COVID-19 Syndrome

Overview

Journal J Med Virol

Specialty Microbiology

Date 2022 May 23

PMID 35603810

Authors

Manoj Sivan

Nick Preston

Amy Parkin

Sophie Makower

Jeremy Gee

Denise Ross

Rachel Tarrant

Jennifer Davison

Stephen Halpin

Rory J OConnor

Mike Horton

Affiliations

Soon will be listed here.

Abstract

Background: The C19-YRS is the literature's first condition-specific, validated scale for patient assessment and monitoring in Post-COVID-19 syndrome (PCS). The 22-item scale's subscales (scores) are symptom severity (0-100), functional disability (0-50), additional symptoms (0-60), and overall health (0-10).

Objectives: This study aimed to test the scale's psychometric properties using Rasch analysis and modify the scale based on analysis findings, emerging information on essential PCS symptoms, and feedback from a working group of patients and professionals.

Methods: Data from 370 PCS patients were assessed using a Rasch Measurement Theory framework to test model fit, local dependency, response category functioning, differential item functioning, targeting, reliability, and unidimensionality. The working group undertook iterative changes to the scale based on the psychometric results and including essential symptoms.

Results: Symptom severity and functional disability subscales showed good targeting and reliability. Post hoc rescoring suggested that a 4-point response category structure would be more appropriate than an 11-point response for both subscales. Symptoms with binary responses were placed in the other symptoms subscale. The overall health single-item subscale remained unchanged.

Conclusion: A 17-item C19-YRSm was developed with subscales (scores): symptom severity (0-30), functional disability (0-15), other symptoms (0-25), and overall health (0-10).

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