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HDL and ASCVD

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Date 2022 May 16
PMID 35575924
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Abstract

In this chapter, we summarize the relationship between circulating high-density lipoprotein (HDL) and atherosclerotic cardiovascular disease (ASCVD). HDL acts in many types of cells, such as endothelial cell, macrophage, T lymphocyte, etc. Recently, novel HDL-related therapies have been developed to treat ASCVD.

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References
1.
Natarajan P, Collier T, Jin Z, Lyass A, Li Y, Ibrahim N . Association of an HDL Apolipoproteomic Score With Coronary Atherosclerosis and Cardiovascular Death. J Am Coll Cardiol. 2019; 73(17):2135-2145. PMC: 6501819. DOI: 10.1016/j.jacc.2019.01.073. View

2.
Janoudi A, Shamoun F, Kalavakunta J, Abela G . Cholesterol crystal induced arterial inflammation and destabilization of atherosclerotic plaque. Eur Heart J. 2015; 37(25):1959-67. DOI: 10.1093/eurheartj/ehv653. View

3.
Choi H, Ruel I, Malina A, Garrod D, Oda M, Pelletier J . Desmocollin 1 is abundantly expressed in atherosclerosis and impairs high-density lipoprotein biogenesis. Eur Heart J. 2017; 39(14):1194-1202. DOI: 10.1093/eurheartj/ehx340. View

4.
Berbee J, Boon M, Khedoe P, Bartelt A, Schlein C, Worthmann A . Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development. Nat Commun. 2015; 6:6356. PMC: 4366535. DOI: 10.1038/ncomms7356. View

5.
Bartelt A, John C, Schaltenberg N, Berbee J, Worthmann A, Cherradi M . Thermogenic adipocytes promote HDL turnover and reverse cholesterol transport. Nat Commun. 2017; 8:15010. PMC: 5399294. DOI: 10.1038/ncomms15010. View