A Survey of Cannabinoids and Toxic Elements in Hemp-derived Products from the United States Marketplace

Overview

Journal J Food Compost Anal

Date 2022 May 13

PMID 35547641

Authors

Geoffrey A Dubrow

Rahul S Pawar

Cynthia Srigley

Jennifer Fong Sam

Christian Talavera

Christine H Parker

Gregory O Noonan

Affiliations

Soon will be listed here.

Abstract

The 2018 Agricultural Improvement Act removed hemp from Schedule I control, creating a market for hemp products, including cannabidiol-containing products. Due to the market's rapid growth, little is known about the presence and concentration of cannabinoids in commercial products. Herein, 11 cannabinoids were quantified using liquid chromatography with diode-array detection in a non-representative sampling of 147 products labeled as containing hemp or cannabidiol. A subset of 133 products were analyzed for toxic elements using inductively coupled plasma-mass spectrometry. Cannabinoid content ranged from < LOD - 143 mg/serving, with a median of 16.7 mg/serving. Fewer than half of products surveyed contained cannabidiol concentrations within 20 % of their label declarations. The estimated exposure to lead was below the Interim Reference Level of 12.5 μg/day Pb for women of childbearing age, and most products presented concentrations of Δ-tetrahydrocannabinol below LOQ. These findings emphasize the need for further testing and representative investigation of the cannabidiol marketplace.

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