Detection of Cofilin MRNA by Hybridization-sensitive Double-stranded Fluorescent Probes

Overview

Journal RSC Adv

Publisher Royal Society of Chemistry

Specialty Chemistry

Date 2022 May 11

PMID 35539109

Authors

Ha Jung Lee

Gui Han Go

Jong Jin Ro

Byeang Hyean Kim

Affiliations

Soon will be listed here.

Abstract

We have developed hybridization-sensitive fluorescent oligonucleotide probes that, in the presence of quencher strands, undergo efficient fluorescence quenching through the formation of partial DNA/DNA duplexes. In the presence of target RNA, rapid displacement of the quencher strands results in highly enhanced fluorescence.

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