The Emerging Roles of N6-methyladenosine (m6A)-modified Long Non-coding RNAs in Human Cancers

Overview

Journal Cell Death Discov

Date 2022 May 9

PMID 35534472

Authors

Jingwen Liu

Wei Zhao

Leyu Zhang

Xi Wang

Affiliations

Soon will be listed here.

Abstract

N-methyladenosine (mA) epitranscriptional modifications widely exist in RNA, which play critical roles in RNA metabolism and biogenesis processes. Long non-coding RNAs (lncRNAs) are class of non-coding RNAs longer than 200 nucleotides without protein-coding ability. LncRNAs participate in a large number of vital biological progressions. With the great improvement of molecular biology, mA and lncRNAs are attracting more attention from researchers and scholars. In this review, we overview the current status of mA and lncRNAs based on the latest research, and propose some viewpoints for future research perspectives.

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