Polyethyleneimine-interlayered Silica-core Quantum Dot-shell Nanocomposites for Sensitive Detection of a Lateral Flow Immunoassay

Overview

Journal RSC Adv

Publisher Royal Society of Chemistry

Specialty Chemistry

Date 2022 May 2

PMID 35496136

Authors

Bo Zhang

Xingsheng Yang

Xiaoxian Liu

Juan Li

Chongwen Wang

Shengqi Wang

Affiliations

Soon will be listed here.

Abstract

Herein, we synthesized high-performance SiO-core quantum dot (QD)-shell nanocomposites (SiO@PEI-QDs) using the polyethyleneimine (PEI)-mediated adsorption method. Cationic PEI was used to form a positively charged interlayer on the SiO core, which achieved a dense adsorption of carboxylated QDs to form a shell of QDs and maintained a good dispersibility of the nanocomposite. The SiO@PEI-QDs showed excellent stability and high luminescence, and served as high-performance fluorescent labels for the detection of bacteria when used with the lateral flow immunoassay (LFA) technique. An SiO@PEI-QD-based LFA strip was successfully applied to rapidly detect in milk samples with a low limit of 5 × 10 cells per mL.

Citing Articles

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