Extracellular Vesicle Therapy for Type 1 Diabetes

Overview

Journal Front Immunol

Specialty Allergy & Immunology

Date 2022 Apr 25

PMID 35464488

Authors

Setareh Soltani

Kamran Mansouri

Mohammad Sajad Emami Aleagha

Narges Moasefi

Niloofar Yavari

Seyed Kazem Shakouri

Sara Notararigo

Ali Shojaeian

Flemming Pociot

Reza Yarani

Affiliations

Soon will be listed here.

Abstract

Type 1 diabetes (T1D) is a chronic disorder characterized by immune-mediated destruction of pancreatic insulin-producing β-cells. The primary treatment for T1D is multiple daily insulin injections to control blood sugar levels. Cell-free delivery packets with therapeutic properties, extracellular vesicles (EVs), mainly from stem cells, have recently gained considerable attention for disease treatments. EVs provide a great potential to treat T1D ascribed to their regenerative, anti-inflammatory, and immunomodulatory effects. Here, we summarize the latest EV applications for T1D treatment and highlight opportunities for further investigation.

Citing Articles

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