Graphene-Based Electrochemical Sensor for Detection of Hepatocellular Carcinoma Markers

Overview

Journal Front Chem

Specialty Chemistry

Date 2022 Apr 25

PMID 35464224

Authors

Ying Liang

Yuan Xu

Yaoyao Tong

Yue Chen

Xilu Chen

Shimin Wu

Affiliations

Soon will be listed here.

Abstract

Hepatocellular carcinoma (HCC) is a group of highly lethal malignant tumors that seriously threaten human health. The main way to improve the survival quality and reduce the mortality of HCC is early diagnosis and treatment. Therefore, it will be of great significance to explore new quantitative detection methods for HCC markers. With the rapid development of electrochemical biosensors and nanomaterials, electrochemical sensors based on graphene can detect tumor markers, with the advantages of simple operation, high detection sensitivity, and specificity. Combined with the published literature in recent years, the article briefly reviews the application of graphene-based electrochemical biosensors in the detection of HCC markers, including alpha-fetoprotein (AFP), Golgi protein-73 (GP73), exosomes, and microRNA-122 (miR-122).

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